eF-site ID 4nck-AB PDB Code 4nck Chain A, B click to enlarge Title Crystal Structure of Pyrococcus furiosis Rad50 R797G mutation Classification DNA BINDING PROTEIN Compound DNA double-strand break repair Rad50 ATPase Source Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (RAD50_PYRFU) Sequence A:  MKLERVTVKNFRSHSDTVVEFKEGINLIIGQNGSGKSSLL DAILVGLYWPLRIKDIKKDEFTKVGARDTYIDLIFEKDGT KYRITRRFLKGYSSGEIHAMKRLVGNEWKHVTEPSSKAIS AFMEKLIPYNIFLNAIYIRQGQIDAILESDEAREKVVREV LNKVKKYKALAREAALSKIGELASEIFAEFTEGKYSEVVV RAEENKVRLFVVWEGKERPLTFLSGGEGIALGLAFRLAMS LYLAGEISLLILDEPTPYLDEERRRKLITIMERYLKKIPQ VILVSHDEELKDAADHVIRISLENGSSKVEVVS B:  MKLERVTVKNFRSHSDTVVEFKEGINLIIGQNGSGKSSLL DAILVGLYWPLRIKDIKKDEFTKVGARDTYIDLIFEKDGT KYRITRRFLEIHAMKRLVGNEWKHVTEPSSKAISAFMEKL IPYNIFLNAIYIRQGQIDAILESDEAREKVVREVLNIEKV KKYKALAREAALSKIGELASEIFAEFTEGKYSEVVVRAEE NKVRLFVVWEGKERPLTFLSGGEGIALGLAFRLAMSLYLA GEISLLILDEPTPYLDEERRRKLITIMERYLKKIPQVILV SHDEELKDAADHVIRISLENGSSKVEVVS Description Functional site 1) chain B residue 50 type sequence P description BINDING SITE FOR RESIDUE SO4 B 901 source : AC1 2) chain B residue 51 type sequence L description BINDING SITE FOR RESIDUE SO4 B 901 source : AC1 3) chain B residue 52 type sequence R description BINDING SITE FOR RESIDUE SO4 B 901 source : AC1 4) chain B residue 53 type sequence I description BINDING SITE FOR RESIDUE SO4 B 901 source : AC1 5) chain B residue 56 type sequence I description BINDING SITE FOR RESIDUE SO4 B 901 source : AC1 6) chain B residue 57 type sequence K description BINDING SITE FOR RESIDUE SO4 B 901 source : AC1 7) chain B residue 58 type sequence K description BINDING SITE FOR RESIDUE SO4 B 901 source : AC1 8) chain B residue 35 type sequence G description BINDING SITE FOR RESIDUE CL B 902 source : AC2 9) chain B residue 36 type sequence K description BINDING SITE FOR RESIDUE CL B 902 source : AC2 10) chain B residue 37 type sequence S description BINDING SITE FOR RESIDUE CL B 902 source : AC2 11) chain B residue 758 type sequence E description BINDING SITE FOR RESIDUE MG B 903 source : AC3 12) chain A residue 763 type BINDING sequence K description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT source Swiss-Prot : SWS_FT_FI3 13) chain A residue 791 type BINDING sequence F description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT source Swiss-Prot : SWS_FT_FI3 14) chain B residue 763 type BINDING sequence K description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT source Swiss-Prot : SWS_FT_FI3 15) chain B residue 791 type BINDING sequence F description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT source Swiss-Prot : SWS_FT_FI3 16) chain A residue 140 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU source Swiss-Prot : SWS_FT_FI2 17) chain B residue 140 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU source Swiss-Prot : SWS_FT_FI2 18) chain A residue 12 type BINDING sequence R description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ source Swiss-Prot : SWS_FT_FI1 19) chain A residue 32 type BINDING sequence N description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ source Swiss-Prot : SWS_FT_FI1 20) chain A residue 60 type BINDING sequence E description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ source Swiss-Prot : SWS_FT_FI1 21) chain B residue 12 type BINDING sequence R description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ source Swiss-Prot : SWS_FT_FI1 22) chain B residue 32 type BINDING sequence N description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ source Swiss-Prot : SWS_FT_FI1 23) chain B residue 60 type BINDING sequence E description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ source Swiss-Prot : SWS_FT_FI1

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