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eF-site ID
|
4nck-A |
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PDB Code
|
4nck |
|
Chain
|
A |
|
click to enlarge
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Title
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Crystal Structure of Pyrococcus furiosis Rad50 R797G mutation |
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Classification
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DNA BINDING PROTEIN |
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Compound
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DNA double-strand break repair Rad50 ATPase |
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Source
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Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (RAD50_PYRFU) |
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Sequence
|
A: |
MKLERVTVKNFRSHSDTVVEFKEGINLIIGQNGSGKSSLL
DAILVGLYWPLRIKDIKKDEFTKVGARDTYIDLIFEKDGT
KYRITRRFLKGYSSGEIHAMKRLVGNEWKHVTEPSSKAIS
AFMEKLIPYNIFLNAIYIRQGQIDAILESDEAREKVVREV
LNKVKKYKALAREAALSKIGELASEIFAEFTEGKYSEVVV
RAEENKVRLFVVWEGKERPLTFLSGGEGIALGLAFRLAMS
LYLAGEISLLILDEPTPYLDEERRRKLITIMERYLKKIPQ
VILVSHDEELKDAADHVIRISLENGSSKVEVVS
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Description
|
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Functional site
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|
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1)
|
chain |
A |
| residue |
763 |
| type |
BINDING |
| sequence |
K
|
| description |
BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
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2)
|
chain |
A |
| residue |
791 |
| type |
BINDING |
| sequence |
F
|
| description |
BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
3)
|
chain |
A |
| residue |
140 |
| type |
BINDING |
| sequence |
Q
|
| description |
BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
A |
| residue |
12 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
32 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
60 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|