eF-site ID 4ncj-D PDB Code 4ncj Chain D click to enlarge Title Crystal Structure of Pyrococcus furiosis Rad50 R805E mutation with ADP Beryllium Flouride Classification DNA BINDING PROTEIN Compound DNA double-strand break repair Rad50 ATPase Source Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (RAD50_PYRFU) Sequence D:  MKLERVTVKNFRSHSDTVVEFKEGINLIIGQNGSGKSSLL DAILVGLYWPLRIKDIKKDEFTKVGARDTYIDLIFEKDGT KYRITRRFLKGYSSGEIHAMKRLVGNEWKHVTEPSSKAIS AFMEKLIPYNIFLNAIYIRQGQIDAILESDEAREKVVREV LNLDTEELIEKVKKYKALAREAALSKIGELASEIFAEFTE GKYSEVVVRAEENKVRLFVVWEGKERPLTFLSGGERIALG LAFELAMSLYLAGEISLLILDEPTPYLDEERRRKLITIME RYLKKIPQVILVSHDEELKDAADHVIRISLENGSSKVEVV S Description Functional site 1) chain D residue 763 type sequence K description BINDING SITE FOR RESIDUE ADP B 901 source : AC4 2) chain D residue 764 type sequence Y description BINDING SITE FOR RESIDUE ADP B 901 source : AC4 3) chain D residue 791 type sequence F description BINDING SITE FOR RESIDUE ADP B 901 source : AC4 4) chain D residue 793 type sequence S description BINDING SITE FOR RESIDUE ADP B 901 source : AC4 5) chain D residue 796 type sequence E description BINDING SITE FOR RESIDUE ADP B 901 source : AC4 6) chain D residue 793 type sequence S description BINDING SITE FOR RESIDUE BEF B 902 source : AC5 7) chain D residue 794 type sequence G description BINDING SITE FOR RESIDUE BEF B 902 source : AC5 8) chain D residue 795 type sequence G description BINDING SITE FOR RESIDUE BEF B 902 source : AC5 9) chain D residue 12 type sequence R description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 10) chain D residue 13 type sequence S description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 11) chain D residue 32 type sequence N description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 12) chain D residue 33 type sequence G description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 13) chain D residue 34 type sequence S description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 14) chain D residue 35 type sequence G description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 15) chain D residue 36 type sequence K description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 16) chain D residue 37 type sequence S description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 17) chain D residue 38 type sequence S description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 18) chain D residue 60 type sequence E description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 19) chain D residue 62 type sequence T description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 20) chain D residue 63 type sequence K description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 21) chain D residue 64 type sequence V description BINDING SITE FOR RESIDUE ADP D 901 source : BC1 22) chain D residue 32 type sequence N description BINDING SITE FOR RESIDUE BEF D 902 source : BC2 23) chain D residue 33 type sequence G description BINDING SITE FOR RESIDUE BEF D 902 source : BC2 24) chain D residue 36 type sequence K description BINDING SITE FOR RESIDUE BEF D 902 source : BC2 25) chain D residue 140 type sequence Q description BINDING SITE FOR RESIDUE BEF D 902 source : BC2 26) chain D residue 37 type sequence S description BINDING SITE FOR RESIDUE MG D 903 source : BC3 27) chain D residue 140 type sequence Q description BINDING SITE FOR RESIDUE MG D 903 source : BC3 28) chain D residue 763 type BINDING sequence K description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT source Swiss-Prot : SWS_FT_FI3 29) chain D residue 791 type BINDING sequence F description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT source Swiss-Prot : SWS_FT_FI3 30) chain D residue 12 type BINDING sequence R description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ source Swiss-Prot : SWS_FT_FI1 31) chain D residue 32 type BINDING sequence N description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ source Swiss-Prot : SWS_FT_FI1 32) chain D residue 60 type BINDING sequence E description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0000269|PubMed:24493214, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU, ECO:0007744|PDB:4NCJ source Swiss-Prot : SWS_FT_FI1 33) chain D residue 140 type BINDING sequence Q description BINDING => ECO:0000269|PubMed:10892749, ECO:0000269|PubMed:21441914, ECO:0007744|PDB:1F2U, ECO:0007744|PDB:3QKT, ECO:0007744|PDB:3QKU source Swiss-Prot : SWS_FT_FI2

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