|
|
eF-site ID
|
4nca-CDEFGH |
|
PDB Code
|
4nca |
|
Chain
|
C, D, E, F, G, H |
|
click to enlarge
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Title
|
Structure of Thermus thermophilus Argonaute bound to guide DNA 19-mer and target DNA in the presence of Mg2+ |
|
Classification
|
NUCLEAR PROTEIN/DNA |
|
Compound
|
Argonaute |
|
Source
|
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (4NCA) |
|
|
Sequence
|
C: |
TGAGGTAGTAGGTTGT
|
| D: |
TACTACCTCG
|
| E: |
TGAGGTAGTAGGTTGT
|
| F: |
TACTACCTCG
|
| G: |
ACAACC
|
| H: |
ACAACC
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
D |
| residue |
10 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE MG A 702
|
| source |
: AC2
|
|
|
2)
|
chain |
G |
| residue |
6 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE MG A 702
|
| source |
: AC2
|
|
|
3)
|
chain |
F |
| residue |
10 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE MG B 702
|
| source |
: AC4
|
|
|
4)
|
chain |
F |
| residue |
10 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE MG B 703
|
| source |
: AC5
|
|
|
5)
|
chain |
H |
| residue |
9 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE MG B 703
|
| source |
: AC5
|
|
|
6)
|
chain |
C |
| residue |
1 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE MG C 101
|
| source |
: AC6
|
|
|
7)
|
chain |
C |
| residue |
3 |
| type |
|
| sequence |
A
|
| description |
BINDING SITE FOR RESIDUE MG C 101
|
| source |
: AC6
|
|
|
8)
|
chain |
D |
| residue |
10 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE MG D 101
|
| source |
: AC7
|
|
|
9)
|
chain |
E |
| residue |
1 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE MG E 101
|
| source |
: AC8
|
|
|
10)
|
chain |
E |
| residue |
3 |
| type |
|
| sequence |
A
|
| description |
BINDING SITE FOR RESIDUE MG E 101
|
| source |
: AC8
|
|
|
|