eF-site ID 4n9f-q PDB Code 4n9f Chain q click to enlarge Title Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Classification LIGASE/VIRAL PROTEIN Compound Cullin-5 Source Homo sapiens (Human) (Q72499_9HIV1) Sequence q:  NRWQVMIVWQVDRMRINTWKRLVKHHMYISRKAKDWFYRH HYESTNPKISSEVHIPLGDAKLVITTYWGLHTGERDWHLG QGVSIEWRKKRYSTQVDPDLADQLIHLHYFDCFSESAIRN TILGRIVSPRCEYQAGHNKVGSLQYLALAALIKPKQIKPP LPSVRKLTE Description Functional site 1) chain q residue 108 type sequence H description BINDING SITE FOR RESIDUE ZN q 201 source : BC2 2) chain q residue 114 type sequence C description BINDING SITE FOR RESIDUE ZN q 201 source : BC2 3) chain q residue 133 type sequence C description BINDING SITE FOR RESIDUE ZN q 201 source : BC2 4) chain q residue 139 type sequence H description BINDING SITE FOR RESIDUE ZN q 201 source : BC2 5) chain q residue 150 type SITE sequence L description Cleavage in virion (by viral protease) => ECO:0000255|HAMAP-Rule:MF_04081 source Swiss-Prot : SWS_FT_FI1 6) chain q residue 96 type MOD_RES sequence T description Phosphothreonine; by host MAP4K1 => ECO:0000255|HAMAP-Rule:MF_04081 source Swiss-Prot : SWS_FT_FI2 7) chain q residue 144 type MOD_RES sequence S description Phosphoserine; by host => ECO:0000255|HAMAP-Rule:MF_04081 source Swiss-Prot : SWS_FT_FI3 8) chain q residue 165 type MOD_RES sequence S description Phosphoserine; by host MAP4K1 => ECO:0000255|HAMAP-Rule:MF_04081 source Swiss-Prot : SWS_FT_FI4

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