eF-site ID 4n9f-M PDB Code 4n9f Chain M click to enlarge Title Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Classification LIGASE/VIRAL PROTEIN Compound Cullin-5 Source Homo sapiens (Human) (Q72499_9HIV1) Sequence M:  ENRWQVMIVWQVDRMRINTWKRLVKHHMYISRKAKDWFYR HHYESTNPKISSEVHIPLGDAKLVITTYWGLHTGERDWHL GQGVSIEWRKKRYSTQVDPDLADQLIHLHYFDCFSESAIR NTILGRIVSPRCEYQAGHNKVGSLQYLALAALIKPKQIKP PLPSVRKLTED Description Functional site 1) chain M residue 108 type sequence H description BINDING SITE FOR RESIDUE ZN M 201 source : AC3 2) chain M residue 114 type sequence C description BINDING SITE FOR RESIDUE ZN M 201 source : AC3 3) chain M residue 133 type sequence C description BINDING SITE FOR RESIDUE ZN M 201 source : AC3 4) chain M residue 139 type sequence H description BINDING SITE FOR RESIDUE ZN M 201 source : AC3 5) chain M residue 114 type BINDING sequence C description BINDING => ECO:0000269|PubMed:24402281, ECO:0000269|PubMed:37640699, ECO:0007744|PDB:4N9F, ECO:0007744|PDB:8FVI source Swiss-Prot : SWS_FT_FI1 6) chain M residue 133 type BINDING sequence C description BINDING => ECO:0000269|PubMed:24402281, ECO:0000269|PubMed:37640699, ECO:0007744|PDB:4N9F, ECO:0007744|PDB:8FVI source Swiss-Prot : SWS_FT_FI1 7) chain M residue 139 type BINDING sequence H description BINDING => ECO:0000269|PubMed:24402281, ECO:0000269|PubMed:37640699, ECO:0007744|PDB:4N9F, ECO:0007744|PDB:8FVI source Swiss-Prot : SWS_FT_FI1 8) chain M residue 108 type BINDING sequence H description BINDING => ECO:0000269|PubMed:24402281, ECO:0000269|PubMed:37640699, ECO:0007744|PDB:4N9F, ECO:0007744|PDB:8FVI source Swiss-Prot : SWS_FT_FI1 9) chain M residue 150 type SITE sequence L description Cleavage in virion (by viral protease) => ECO:0000255|HAMAP-Rule:MF_04081, ECO:0000269|PubMed:12186895 source Swiss-Prot : SWS_FT_FI2 10) chain M residue 96 type MOD_RES sequence T description Phosphothreonine; by host MAP4K1 => ECO:0000255|HAMAP-Rule:MF_04081 source Swiss-Prot : SWS_FT_FI3 11) chain M residue 144 type MOD_RES sequence S description Phosphoserine; by host => ECO:0000255|HAMAP-Rule:MF_04081 source Swiss-Prot : SWS_FT_FI4 12) chain M residue 165 type MOD_RES sequence S description Phosphoserine; by host MAP4K1 => ECO:0000255|HAMAP-Rule:MF_04081 source Swiss-Prot : SWS_FT_FI5

Display surface Download Links