eF-site ID 4n9f-7 PDB Code 4n9f Chain 7 click to enlarge Title Crystal structure of the Vif-CBFbeta-CUL5-ElOB-ElOC pentameric complex Classification LIGASE/VIRAL PROTEIN Compound Cullin-5 Source Homo sapiens (Human) (Q72499_9HIV1) Sequence 7:  NRWQVMIVWQVDRMRINTWKRLVKHHMYISRKAKDWFYRH HYESTNPKISSEVHIPLGDAKLVITTYWGLHTGERDWHLG QGVSIEWRKKRYSTQVDPDLADQLIHLHYFDCFSESAIRN TILGRIVSPRCEYQAGHNKVGSLQYLALAALIKPKQIKPP LPSVRKLTED Description Functional site 1) chain 7 residue 108 type sequence H description BINDING SITE FOR RESIDUE ZN 7 201 source : BC1 2) chain 7 residue 114 type sequence C description BINDING SITE FOR RESIDUE ZN 7 201 source : BC1 3) chain 7 residue 133 type sequence C description BINDING SITE FOR RESIDUE ZN 7 201 source : BC1 4) chain 7 residue 134 type sequence E description BINDING SITE FOR RESIDUE ZN 7 201 source : BC1 5) chain 7 residue 139 type sequence H description BINDING SITE FOR RESIDUE ZN 7 201 source : BC1 6) chain 7 residue 108 type BINDING sequence H description BINDING => ECO:0000269|PubMed:24402281, ECO:0000269|PubMed:37640699, ECO:0007744|PDB:4N9F, ECO:0007744|PDB:8FVI source Swiss-Prot : SWS_FT_FI1 7) chain 7 residue 114 type BINDING sequence C description BINDING => ECO:0000269|PubMed:24402281, ECO:0000269|PubMed:37640699, ECO:0007744|PDB:4N9F, ECO:0007744|PDB:8FVI source Swiss-Prot : SWS_FT_FI1 8) chain 7 residue 133 type BINDING sequence C description BINDING => ECO:0000269|PubMed:24402281, ECO:0000269|PubMed:37640699, ECO:0007744|PDB:4N9F, ECO:0007744|PDB:8FVI source Swiss-Prot : SWS_FT_FI1 9) chain 7 residue 139 type BINDING sequence H description BINDING => ECO:0000269|PubMed:24402281, ECO:0000269|PubMed:37640699, ECO:0007744|PDB:4N9F, ECO:0007744|PDB:8FVI source Swiss-Prot : SWS_FT_FI1 10) chain 7 residue 150 type SITE sequence L description Cleavage in virion (by viral protease) => ECO:0000255|HAMAP-Rule:MF_04081, ECO:0000269|PubMed:12186895 source Swiss-Prot : SWS_FT_FI2 11) chain 7 residue 96 type MOD_RES sequence T description Phosphothreonine; by host MAP4K1 => ECO:0000255|HAMAP-Rule:MF_04081 source Swiss-Prot : SWS_FT_FI3 12) chain 7 residue 144 type MOD_RES sequence S description Phosphoserine; by host => ECO:0000255|HAMAP-Rule:MF_04081 source Swiss-Prot : SWS_FT_FI4 13) chain 7 residue 165 type MOD_RES sequence S description Phosphoserine; by host MAP4K1 => ECO:0000255|HAMAP-Rule:MF_04081 source Swiss-Prot : SWS_FT_FI5

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