|
eF-site ID
|
4n19-A |
PDB Code
|
4n19 |
Chain
|
A |
|
click to enlarge
|
|
Title
|
Structural basis of conformational transitions in the active site and 80 s loop in the FK506 binding protein FKBP12 |
Classification
|
ISOMERASE |
Compound
|
Peptidyl-prolyl cis-trans isomerase FKBP1A |
Source
|
Homo sapiens (Human) (FKB1A_HUMAN) |
|
Sequence
|
A: |
GVQVETISPGDGRTFPKRGQTVVVHYTGMLEDGKKFDSSR
DRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDY
AYGATGHPPIIPPHATLVFDVELLKLE
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
A |
residue |
83 |
type |
|
sequence |
G
|
description |
BINDING SITE FOR RESIDUE SO4 A 201
|
source |
: AC1
|
|
2)
|
chain |
A |
residue |
84 |
type |
|
sequence |
A
|
description |
BINDING SITE FOR RESIDUE SO4 A 201
|
source |
: AC1
|
|
3)
|
chain |
A |
residue |
84 |
type |
|
sequence |
A
|
description |
BINDING SITE FOR RESIDUE SO4 A 201
|
source |
: AC1
|
|
4)
|
chain |
A |
residue |
85 |
type |
|
sequence |
T
|
description |
BINDING SITE FOR RESIDUE SO4 A 201
|
source |
: AC1
|
|
5)
|
chain |
A |
residue |
26 |
type |
catalytic |
sequence |
Y
|
description |
362
|
source |
MCSA : MCSA1
|
|
6)
|
chain |
A |
residue |
36 |
type |
catalytic |
sequence |
F
|
description |
362
|
source |
MCSA : MCSA1
|
|
7)
|
chain |
A |
residue |
37 |
type |
catalytic |
sequence |
D
|
description |
362
|
source |
MCSA : MCSA1
|
|
8)
|
chain |
A |
residue |
56 |
type |
catalytic |
sequence |
I
|
description |
362
|
source |
MCSA : MCSA1
|
|
9)
|
chain |
A |
residue |
82 |
type |
catalytic |
sequence |
Y
|
description |
362
|
source |
MCSA : MCSA1
|
|
10)
|
chain |
A |
residue |
99 |
type |
catalytic |
sequence |
F
|
description |
362
|
source |
MCSA : MCSA1
|
|
11)
|
chain |
A |
residue |
52 |
type |
MOD_RES |
sequence |
K
|
description |
N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P26883
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|