eF-site ID 4n19-A
PDB Code 4n19
Chain A

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Title Structural basis of conformational transitions in the active site and 80 s loop in the FK506 binding protein FKBP12
Classification ISOMERASE
Compound Peptidyl-prolyl cis-trans isomerase FKBP1A
Source Homo sapiens (Human) (FKB1A_HUMAN)
Sequence A:  GVQVETISPGDGRTFPKRGQTVVVHYTGMLEDGKKFDSSR
DRNKPFKFMLGKQEVIRGWEEGVAQMSVGQRAKLTISPDY
AYGATGHPPIIPPHATLVFDVELLKLE
Description


Functional site

1) chain A
residue 83
type
sequence G
description BINDING SITE FOR RESIDUE SO4 A 201
source : AC1

2) chain A
residue 84
type
sequence A
description BINDING SITE FOR RESIDUE SO4 A 201
source : AC1

3) chain A
residue 84
type
sequence A
description BINDING SITE FOR RESIDUE SO4 A 201
source : AC1

4) chain A
residue 85
type
sequence T
description BINDING SITE FOR RESIDUE SO4 A 201
source : AC1

5) chain A
residue 52
type MOD_RES
sequence K
description N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P26883
source Swiss-Prot : SWS_FT_FI1

6) chain A
residue 26
type catalytic
sequence Y
description 362
source MCSA : MCSA1

7) chain A
residue 36
type catalytic
sequence F
description 362
source MCSA : MCSA1

8) chain A
residue 37
type catalytic
sequence D
description 362
source MCSA : MCSA1

9) chain A
residue 56
type catalytic
sequence I
description 362
source MCSA : MCSA1

10) chain A
residue 82
type catalytic
sequence Y
description 362
source MCSA : MCSA1

11) chain A
residue 99
type catalytic
sequence F
description 362
source MCSA : MCSA1


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