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eF-site ID
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4mq9-F |
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PDB Code
|
4mq9 |
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Chain
|
F |
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click to enlarge
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Title
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Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with GE23077 |
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Classification
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TRANSCRIPTION, TRANSFERASE/ANTIBIOTIC |
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Compound
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DNA-directed RNA polymerase subunit alpha |
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Source
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ORGANISM_SCIENTIFIC: Thermus thermophilus; |
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Sequence
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F: |
SDPVRQYLHEIGQVPLLTLEEEVELARKVEEGMEAIKKLS
EITGLDPDLIREVVRAKILGSARVRHTLDPKTVEEIDQKL
KSLPKEHKRYLHIAREGEAARQHLIEANLRLVVSIAKKYT
GRGLSFLDLIQEGNQGLIRAVEKFEYKRRFKFSTYATWWI
RQAINRAIADQARTIRIPVHMVETINKLSRTARQLQQELG
REPTYEEIAEAMGPGWDAKRVEETLKIAQEPVSLETPIGD
EKDSFYGDFIPDEHLPSPVDAATQSLLSEELEKALSKLSE
REAMVLKLRKGLIDGREHTLEEVGAFFGVTRERIRQIENK
ALRKLKYHESRTRKLRDFL
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Description
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Functional site
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1)
|
chain |
F |
| residue |
382-408 |
| type |
prosite |
| sequence |
TLEEVGAFFGVTRERIRQIENKALRKL
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| description |
SIGMA70_2 Sigma-70 factors family signature 2. TleEVGaffgVTrerIrQIEnkaLrkL
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| source |
prosite : PS00716
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2)
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chain |
F |
| residue |
187-194 |
| type |
prosite |
| sequence |
LIEANLRL
|
| description |
CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LIEANLRL
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| source |
prosite : PS00867
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