|
|
eF-site ID
|
4mnq-E |
|
PDB Code
|
4mnq |
|
Chain
|
E |
|
click to enlarge
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|
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Title
|
TCR-peptide specificity overrides affinity enhancing TCR-MHC interactions |
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Classification
|
IMMUNE SYSTEM |
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Compound
|
HLA class I histocompatibility antigen, A-2 alpha chain |
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Source
|
Homo sapiens (Human) (TRBC1_HUMAN) |
|
|
Sequence
|
E: |
AGVTQTPKFQVLKTGQSMTLQCAQDMNHEYMSWYRQDPGM
GLRLIHYSIHPEYTDQGEVPNGYNVSRSTTEDFPLRLLSA
APSQTSVYFCASSYQGTEAFFGQGTRLTVVEDLNKVFPPE
VAVFEPSEAEISHTQKATLVCLATGFYPDHVELSWWVNGK
EVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSATFWQDP
RNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAEAWGRAD
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|
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Description
|
(1) |
HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Telomerase reverse transcriptase (E.C.2.7.7.49), Uncharacterized protein, T-cell receptor, sp3.4 alpha chain, V_segment translation product, T-cell receptor beta-1 chain C region
|
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Functional site
|
|
|
1)
|
chain |
E |
| residue |
163 |
| type |
|
| sequence |
V
|
| description |
BINDING SITE FOR RESIDUE EDO E 301
|
| source |
: AC3
|
|
|
2)
|
chain |
E |
| residue |
164 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE EDO E 301
|
| source |
: AC3
|
|
|
3)
|
chain |
E |
| residue |
165 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE EDO E 301
|
| source |
: AC3
|
|
|
4)
|
chain |
E |
| residue |
65 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
E |
| residue |
180 |
| type |
CARBOHYD |
| sequence |
L
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|