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|
eF-site ID
|
4mnq-B |
|
PDB Code
|
4mnq |
|
Chain
|
B |
|
click to enlarge
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Title
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TCR-peptide specificity overrides affinity enhancing TCR-MHC interactions |
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Classification
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IMMUNE SYSTEM |
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Compound
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HLA class I histocompatibility antigen, A-2 alpha chain |
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Source
|
Homo sapiens (Human) (TRBC1_HUMAN) |
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Sequence
|
B: |
MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDL
LKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYA
CRVNHVTLSQPKIVKWDRDM
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Description
|
(1) |
HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, Telomerase reverse transcriptase (E.C.2.7.7.49), Uncharacterized protein, T-cell receptor, sp3.4 alpha chain, V_segment translation product, T-cell receptor beta-1 chain C region
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Functional site
|
|
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1)
|
chain |
B |
| residue |
19 |
| type |
CARBOHYD |
| sequence |
K
|
| description |
N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
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2)
|
chain |
B |
| residue |
41 |
| type |
CARBOHYD |
| sequence |
K
|
| description |
N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
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3)
|
chain |
B |
| residue |
48 |
| type |
CARBOHYD |
| sequence |
K
|
| description |
N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
B |
| residue |
58 |
| type |
CARBOHYD |
| sequence |
K
|
| description |
N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
B |
| residue |
91 |
| type |
CARBOHYD |
| sequence |
K
|
| description |
N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
B |
| residue |
94 |
| type |
CARBOHYD |
| sequence |
K
|
| description |
N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
B |
| residue |
78-84 |
| type |
prosite |
| sequence |
YACRVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH
|
| source |
prosite : PS00290
|
|
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8)
|
chain |
B |
| residue |
1 |
| type |
CARBOHYD |
| sequence |
I
|
| description |
N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269|PubMed:7918443
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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9)
|
chain |
B |
| residue |
2 |
| type |
MOD_RES |
| sequence |
Q
|
| description |
Pyrrolidone carboxylic acid; in form pI 5.3 => ECO:0000269|PubMed:7554280
|
| source |
Swiss-Prot : SWS_FT_FI1
|
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