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eF-site ID
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4m6b-ACDF |
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PDB Code
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4m6b |
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Chain
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A, C, D, F |
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click to enlarge
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Title
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Crystal structure of yeast Swr1-Z domain in complex with H2A.Z-H2B dimer |
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Classification
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Structural Protein/Hydrolase |
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Compound
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Chimera protein of Histone H2B.1 and Histone H2A.Z |
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Source
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Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (SWR1_YEAST) |
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Sequence
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A: |
KETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERI
ATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSE
GTRAVTKYSSSTQAQSSSARAGLQFPVGRIKRYLKRHATG
RTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRIT
PRHLQLAIRGDDELDSLIRATIASG
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| C: |
SVGLSALFDLDLDDSEDFTVNSS
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| D: |
RKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFER
IATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVS
EGTRAVTKYSSSTQAQSSSARAGLQFPVGRIKRYLKRHAT
GRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRI
TPRHLQLAIRGDDELDSLIRATIASGG
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| F: |
SVGLSALFDLDLDDSEDFTVNSS
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Description
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Functional site
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1)
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chain |
A |
| residue |
37 |
| type |
MOD_RES |
| sequence |
K
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| description |
N6,N6-dimethyllysine => ECO:0000269|PubMed:19113941
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
D |
| residue |
37 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6,N6-dimethyllysine => ECO:0000269|PubMed:19113941
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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3)
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chain |
A |
| residue |
46 |
| type |
MOD_RES |
| sequence |
K
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| description |
N6-succinyllysine => ECO:0000269|PubMed:22389435
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| source |
Swiss-Prot : SWS_FT_FI2
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4)
|
chain |
D |
| residue |
46 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-succinyllysine => ECO:0000269|PubMed:22389435
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| source |
Swiss-Prot : SWS_FT_FI2
|
|
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5)
|
chain |
A |
| residue |
137-143 |
| type |
prosite |
| sequence |
AGLQFPV
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| description |
HISTONE_H2A Histone H2A signature. AGLqFPV
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| source |
prosite : PS00046
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6)
|
chain |
A |
| residue |
95-117 |
| type |
prosite |
| sequence |
REIQTAVRLILPGELAKHAVSEG
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| description |
HISTONE_H2B Histone H2B signature. REIQTavRlILpGELaKHAVSEG
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| source |
prosite : PS00357
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7)
|
chain |
A |
| residue |
123 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:10642555, ECO:0000269|PubMed:12535538, ECO:0000269|PubMed:12535539, ECO:0000269|PubMed:14660635, ECO:0000269|PubMed:15280549, ECO:0000269|PubMed:16432255
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| source |
Swiss-Prot : SWS_FT_FI3
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8)
|
chain |
D |
| residue |
123 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:10642555, ECO:0000269|PubMed:12535538, ECO:0000269|PubMed:12535539, ECO:0000269|PubMed:14660635, ECO:0000269|PubMed:15280549, ECO:0000269|PubMed:16432255
|
| source |
Swiss-Prot : SWS_FT_FI3
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