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eF-site ID
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4ltc-G |
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PDB Code
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4ltc |
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Chain
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G |
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click to enlarge
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Title
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Crystal structure of yeast 20S proteasome in complex with enone carmaphycin analogue 6 |
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Classification
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Hydrolase/Hydrolase Inhibitor |
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Compound
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Proteasome subunit alpha type-2 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
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G: |
AGYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKD
CTVVISQKKVPDKLLDPTTVSYIFCISRTIGMVVNGPIPD
ARNAALRAKAEAAEFRYKYGYDMPCDVLAKRMANLSQIYT
QRAYMRPLGVILTFVSVDEELGPSIYKTDPAGYYVGYKAT
ATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITH
MIDALGTEFSKNDLEVGVATKDKFFTLSAENIEERLVAIA
EQD
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Description
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(1) |
Proteasome subunit alpha type-2 (E.C.3.4.25.1), Proteasome subunit alpha type-3 (E.C.3.4.25.1), Proteasome subunit alpha type-4 (E.C.3.4.25.1), Proteasome subunit alpha type-5 (E.C.3.4.25.1), Proteasome subunit alpha type-6 (E.C.3.4.25.1), Probable proteasome subunit alpha type-7 (E.C.3.4.25.1), Proteasome subunit alpha type-1 (E.C.3.4.25.1), Proteasome subunit beta type-2 (E.C.3.4.25.1), Proteasome subunit beta type-3 (E.C.3.4.25.1), Proteasome subunit beta type-4 (E.C.3.4.25.1), Proteasome subunit beta type-5 (E.C.3.4.25.1), Proteasome subunit beta type-6 (E.C.3.4.25.1), Proteasome subunit beta type-7 (E.C.3.4.25.1), Proteasome subunit beta type-1 (E.C.3.4.25.1)
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Functional site
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1)
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chain |
G |
| residue |
223 |
| type |
CROSSLNK |
| sequence |
K
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| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
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| source |
Swiss-Prot : SWS_FT_FI3
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2)
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chain |
G |
| residue |
3-25 |
| type |
prosite |
| sequence |
YDRHITIFSPEGRLYQVEYAFKA
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| description |
PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdralSiFSPdGHifQVEYAleA
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| source |
prosite : PS00388
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