eF-site ID 4lmp-A PDB Code 4lmp Chain A click to enlarge Title Mycobacterium tuberculosis L-alanine dehydrogenase x-ray structure in complex with N6-methyl adenosine Classification OXIDOREDUCTASE Compound Alanine dehydrogenase Source Mycobacterium tuberculosis H37Rv (I6YEC9_MYCTU) Sequence A:  MRVGIPTETKNNEFRVAITPAGVAELTRRGHEVLIQAGAG EGSAITDADFKAAGAQLVGTADQVWADADLLLKVKEPIAA EYGRLRHGQILFTFLHLAASRACTDALLDSGTTSIAYETV QTADGALPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLM GGVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDIN IDKLRQLDAEFCGRIHTRYSSAYELEGAVKRADLVIGAVL VPGAKAPKLVSNSLVAHMKPGAVLVDIAIDQGGCFEGSRP TTYDHPTFAVHDTLFYCVANMPASVPKTSTYALTNATMPY VLELADHGWRAACRSNPALAKGLSTHEGALLSERVATDLG VPFTEPASVLA Description Functional site 1) chain A residue 197 type sequence L description BINDING SITE FOR RESIDUE 6MD A 401 source : AC1 2) chain A residue 198 type sequence D description BINDING SITE FOR RESIDUE 6MD A 401 source : AC1 3) chain A residue 203 type sequence K description BINDING SITE FOR RESIDUE 6MD A 401 source : AC1 4) chain A residue 220 type sequence S description BINDING SITE FOR RESIDUE 6MD A 401 source : AC1 5) chain A residue 239 type sequence V description BINDING SITE FOR RESIDUE 6MD A 401 source : AC1 6) chain A residue 240 type sequence L description BINDING SITE FOR RESIDUE 6MD A 401 source : AC1 7) chain A residue 249 type sequence L description BINDING SITE FOR RESIDUE 6MD A 401 source : AC1 8) chain A residue 177 type sequence G description BINDING SITE FOR RESIDUE GOL A 402 source : AC2 9) chain A residue 178 type sequence T description BINDING SITE FOR RESIDUE GOL A 402 source : AC2 10) chain A residue 179 type sequence A description BINDING SITE FOR RESIDUE GOL A 402 source : AC2 11) chain A residue 130 type sequence L description BINDING SITE FOR RESIDUE GOL A 403 source : AC3 12) chain A residue 134 type sequence S description BINDING SITE FOR RESIDUE GOL A 403 source : AC3 13) chain A residue 240 type sequence L description BINDING SITE FOR RESIDUE GOL A 403 source : AC3 14) chain A residue 267 type sequence I description BINDING SITE FOR RESIDUE GOL A 403 source : AC3 15) chain A residue 302 type sequence P description BINDING SITE FOR RESIDUE GOL A 403 source : AC3 16) chain A residue 116 type sequence A description BINDING SITE FOR RESIDUE GOL A 404 source : AC4 17) chain A residue 119 type sequence T description BINDING SITE FOR RESIDUE GOL A 404 source : AC4 18) chain A residue 341 type sequence K description BINDING SITE FOR RESIDUE GOL A 404 source : AC4 19) chain A residue 342 type sequence G description BINDING SITE FOR RESIDUE GOL A 404 source : AC4 20) chain A residue 343 type sequence L description BINDING SITE FOR RESIDUE GOL A 404 source : AC4 21) chain A residue 344 type sequence S description BINDING SITE FOR RESIDUE GOL A 404 source : AC4 22) chain A residue 352 type sequence S description BINDING SITE FOR RESIDUE GOL A 404 source : AC4 23) chain A residue 354 type sequence R description BINDING SITE FOR RESIDUE GOL A 404 source : AC4 24) chain A residue 355 type sequence V description BINDING SITE FOR RESIDUE GOL A 404 source : AC4 25) chain A residue 126 type sequence A description BINDING SITE FOR RESIDUE GOL A 405 source : AC5 26) chain A residue 127 type sequence L description BINDING SITE FOR RESIDUE GOL A 405 source : AC5 27) chain A residue 131 type sequence A description BINDING SITE FOR RESIDUE GOL A 405 source : AC5 28) chain A residue 134 type sequence S description BINDING SITE FOR RESIDUE GOL A 405 source : AC5 29) chain A residue 178 type sequence T description BINDING SITE FOR RESIDUE GOL A 405 source : AC5 30) chain A residue 156 type sequence R description BINDING SITE FOR RESIDUE SO4 A 406 source : AC6 31) chain A residue 259 type sequence K description BINDING SITE FOR RESIDUE SO4 A 406 source : AC6 32) chain A residue 307 type sequence K description BINDING SITE FOR RESIDUE SO4 A 406 source : AC6 33) chain A residue 59 type sequence G description BINDING SITE FOR RESIDUE SO4 A 407 source : AC7 34) chain A residue 60 type sequence T description BINDING SITE FOR RESIDUE SO4 A 407 source : AC7 35) chain A residue 61 type sequence A description BINDING SITE FOR RESIDUE SO4 A 407 source : AC7 36) chain A residue 62 type sequence D description BINDING SITE FOR RESIDUE SO4 A 407 source : AC7 37) chain A residue 63 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 407 source : AC7 38) chain A residue 84 type sequence R description BINDING SITE FOR RESIDUE SO4 A 407 source : AC7 39) chain A residue 15 type sequence R description BINDING SITE FOR RESIDUE SO4 A 408 source : AC8 40) chain A residue 75 type sequence K description BINDING SITE FOR RESIDUE SO4 A 408 source : AC8 41) chain A residue 133 type sequence M description BINDING SITE FOR RESIDUE SO4 A 408 source : AC8 42) chain A residue 300 type sequence N description BINDING SITE FOR RESIDUE SO4 A 408 source : AC8 43) chain A residue 302 type sequence P description BINDING SITE FOR RESIDUE SO4 A 408 source : AC8 44) chain A residue 4-30 type prosite sequence GIPTETKNNEFRVAITPAGVAELTRRG description ALADH_PNT_1 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. GIPtEtknNEf..RVAiTPaGVaeLtRrG source prosite : PS00836 45) chain A residue 173-198 type prosite sequence VIGAGTAGYNAARIANGMGATVTVLD description ALADH_PNT_2 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. VIGAGtAGynAariAnGMGAtVtvlD source prosite : PS00837

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