eF-site ID 4lk1-J PDB Code 4lk1 Chain J click to enlarge Title Crystal Structure Analysis of the E.coli holoenzyme Classification TRANSFERASE Compound DNA-directed RNA polymerase subunit alpha Source Escherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1) (RPOD_ECOLI) Sequence J:  EFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDG LFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQT KVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDI ERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDE FDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRK KLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPL DGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNE KRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQ GRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALE LFKPFIYGKLELRGLATTIKAAKKMVEREEAVVWDILDEV IREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCA AYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPAN GEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAER LYRSGLASLHARVKVRITEYEKDANGELVAKTSLKDTTVG RAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLK PTVIFADQIMYTGFAYAARSGASVGIDDMVIPEKKHEIIS EAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSK AMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAA QIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFIS THGARKGLADTALKTANSGYLTRRLVDVAQDLVVTEDDCG THEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTAD ILVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVC AHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTSSIQ VKNKGSIKLSNVKSVVNSSGKLVITSRNTELKLIDEFGRT KESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEV SGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGG KDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLED GVQISSGDTLARIPQGLPRVADLFEARRPKEPAILAEISG IVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEG ERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVY RLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQVE YSRVKIANRELEANGKVGATYSRDLLGITKASLATESFIS AASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGT GYAYHQDRMRRRAA Description Functional site 1) chain J residue 460 type sequence D description BINDING SITE FOR RESIDUE MG J 1501 source : AC4 2) chain J residue 462 type sequence D description BINDING SITE FOR RESIDUE MG J 1501 source : AC4 3) chain J residue 464 type sequence D description BINDING SITE FOR RESIDUE MG J 1501 source : AC4 4) chain J residue 70 type sequence C description BINDING SITE FOR RESIDUE ZN J 1502 source : AC5 5) chain J residue 72 type sequence C description BINDING SITE FOR RESIDUE ZN J 1502 source : AC5 6) chain J residue 85 type sequence C description BINDING SITE FOR RESIDUE ZN J 1502 source : AC5 7) chain J residue 88 type sequence C description BINDING SITE FOR RESIDUE ZN J 1502 source : AC5 8) chain J residue 814 type sequence C description BINDING SITE FOR RESIDUE ZN J 1503 source : AC6 9) chain J residue 888 type sequence C description BINDING SITE FOR RESIDUE ZN J 1503 source : AC6 10) chain J residue 895 type sequence C description BINDING SITE FOR RESIDUE ZN J 1503 source : AC6 11) chain J residue 898 type sequence C description BINDING SITE FOR RESIDUE ZN J 1503 source : AC6

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