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eF-site ID
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4lk1-C |
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PDB Code
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4lk1 |
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Chain
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C |
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click to enlarge
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Title
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Crystal Structure Analysis of the E.coli holoenzyme |
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Classification
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TRANSFERASE |
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Compound
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DNA-directed RNA polymerase subunit alpha |
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Source
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Escherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1) (RPOD_ECOLI) |
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Sequence
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C: |
YSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQD
PEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDV
QECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEV
YMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSDKG
KTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRR
KLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQMELV
PERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDV
KLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLL
AKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSA
LVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAVGR
MKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEV
DDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLSLG
DLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLS
EITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIE
TPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDE
IHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKGES
SLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGG
VVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQN
TCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNMRV
AFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRD
TKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGGDI
LVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPN
GVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSE
ELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGL
TDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGDDL
APGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPI
EDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAK
GIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLS
TFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLG
DLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDK
MHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYG
AAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPES
FNVLLKEIRSLGINIELEDE
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Description
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Functional site
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1)
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chain |
C |
| residue |
1063-1075 |
| type |
prosite |
| sequence |
GDKMAGRHGNKGV
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| description |
RNA_POL_BETA RNA polymerases beta chain signature. GdKMAGrHGNKGV
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| source |
prosite : PS01166
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