eF-site ID 4lk0-D PDB Code 4lk0 Chain D click to enlarge Title Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex Classification TRANSFERASE Compound DNA-directed RNA polymerase subunit alpha Source Escherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1) (VRPI_BPT7) Sequence D:  LKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYR TFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEK CGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLL LDMPLRDIERVLYFESYVVIEGGMTNLERQQILTEEQYLD ALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNE TNSETKRKKLTKRIKLLEAFVQSGNKPEWMILTVLPVLPP DLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAA PDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSL ADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCG LPKKMALELFKPFIYGKLELRGLATTIKAAKKMVEREEAV VWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAI QLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMST NNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVL TGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAKT SLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNT CYRILGLKPTVIFADQIMYTGFAYAARSGASVGIDDMVIP EKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWA AANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMAD SGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGL NVLQYFISTHGARKGLADTALKTANSGYLTRRLVDVAQDL VVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAED VLKPGTADILVPRNTLLHEQWCDLLEENSVDAVKVRSVVS CDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPG TQLTSSIQVKNKGSIKLSNVKSVVNSSGKLVITSRNTELK LIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPH TMPVITEVSGFVRFTDMIDGQTITRQTDELTGLSSLVVLD SAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPG KAIVQLEDGVQISSGDTLARIPQTGGLPRVADLFEARRPK EPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIP KWRQLNVFEGERVERGDVISDGPEAPHDILRLRGVHAVTR YIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGS SDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITK ASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENV IVGRLIPAGTGYAYHQDRMRRRAAG Description Functional site 1) chain D residue 460 type sequence D description BINDING SITE FOR RESIDUE MG D 1501 source : AC1 2) chain D residue 462 type sequence D description BINDING SITE FOR RESIDUE MG D 1501 source : AC1 3) chain D residue 70 type sequence C description BINDING SITE FOR RESIDUE ZN D 1502 source : AC2 4) chain D residue 72 type sequence C description BINDING SITE FOR RESIDUE ZN D 1502 source : AC2 5) chain D residue 85 type sequence C description BINDING SITE FOR RESIDUE ZN D 1502 source : AC2 6) chain D residue 88 type sequence C description BINDING SITE FOR RESIDUE ZN D 1502 source : AC2 7) chain D residue 814 type sequence C description BINDING SITE FOR RESIDUE ZN D 1503 source : AC3 8) chain D residue 888 type sequence C description BINDING SITE FOR RESIDUE ZN D 1503 source : AC3 9) chain D residue 895 type sequence C description BINDING SITE FOR RESIDUE ZN D 1503 source : AC3 10) chain D residue 898 type sequence C description BINDING SITE FOR RESIDUE ZN D 1503 source : AC3

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