eF-site ID 4ljz-J PDB Code 4ljz Chain J click to enlarge Title Crystal Structure Analysis of the E.coli holoenzyme Classification TRANSFERASE Compound DNA-directed RNA polymerase subunit alpha Source Escherichia coli (strain ATCC 33849 / DSM 4235 / NCIB 12045 / K12 / DH1) (RPOD_ECOLI) Sequence J:  EFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDG LFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQT KVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDI ERVLYFESYVVIEGGMTNLERQQILTEEQYLDALEEFGDE FDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRK KLTKRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPL DGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNE KRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGLG KRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGK LELRGLATTIKAAKKMVEREEAVVWDILDEVIREHPVLLN RAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGD QMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQ DVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASL HARVKVRITEYEKDANGELVAKTSLKDTTVGRAILWMIVP KGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQI MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEI QEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTE TVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQLAGMR GLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLA DTALKTANSGYLTRRLVDVAQDLVVTEDDCGTHEGIMMTP VIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLL HEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLA RGHIINKGEAIGVIAAQSIGEPGTQLTSSIQVKNKGSIKL SNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYG AVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDM IDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKI VDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDT LARIPQGLPRVADLFEARRPKEPAILAEISGIVSFGKETK GKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERVERGDVI SDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKIND KHIEVIVRQMLRKATIVNAGSSDFLEGEQVEYSRVKIANR ELEANGKVGATYSRDLLGITKASLATESFISAASFQETTR VLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRM RRRAA Description Functional site 1) chain J residue 460 type sequence D description BINDING SITE FOR RESIDUE MG J 1501 source : AC4 2) chain J residue 462 type sequence D description BINDING SITE FOR RESIDUE MG J 1501 source : AC4 3) chain J residue 464 type sequence D description BINDING SITE FOR RESIDUE MG J 1501 source : AC4 4) chain J residue 70 type sequence C description BINDING SITE FOR RESIDUE ZN J 1502 source : AC5 5) chain J residue 72 type sequence C description BINDING SITE FOR RESIDUE ZN J 1502 source : AC5 6) chain J residue 85 type sequence C description BINDING SITE FOR RESIDUE ZN J 1502 source : AC5 7) chain J residue 88 type sequence C description BINDING SITE FOR RESIDUE ZN J 1502 source : AC5 8) chain J residue 814 type sequence C description BINDING SITE FOR RESIDUE ZN J 1503 source : AC6 9) chain J residue 888 type sequence C description BINDING SITE FOR RESIDUE ZN J 1503 source : AC6 10) chain J residue 895 type sequence C description BINDING SITE FOR RESIDUE ZN J 1503 source : AC6 11) chain J residue 898 type sequence C description BINDING SITE FOR RESIDUE ZN J 1503 source : AC6

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