eF-site ID 4lc5-AB PDB Code 4lc5 Chain A, B click to enlarge Title Structural basis of substrate specificity of CDA superfamily guanine deaminase Classification HYDROLASE Compound Cytidine and deoxycytidylate deaminase zinc-binding region Source Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298) (Q82Y41_NITEU) Sequence A:  MNDALHIGLPPFLVQANNEPRVLAAPEARMGYVLELVRAN IAADGGPFAAAVFERDSGLLIAAGTNRVVPGRCSAAHAEI LALSLAQAKLDTHDLSADGLPACELVTSAEPCVMCFGAVI WSGVRSLVCAARSDDVEAIGFDEGPRPENWMGGLEARGIT VTTGLLRDAACALLREYNACNGVIYNARC B:  GHMNDALHIGLPPFLVQANNEPRVLAAPEARMGYVLELVR ANIAADGGPFAAAVFERDSGLLIAAGTNRVVPGRCSAAHA EILALSLAQAKLDTHDLSADGLPACELVTSAEPCVMCFGA VIWSGVRSLVCAARSDDVEAIGFDEGPRPENWMGGLEARG ITVTTGLLRDAACALLREYNAC Description (1)  Cytidine and deoxycytidylate deaminase zinc-binding region Functional site 1) chain A residue 77 type sequence H description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 2) chain A residue 112 type sequence C description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 3) chain A residue 115 type sequence C description BINDING SITE FOR RESIDUE ZN A 201 source : AC1 4) chain A residue 48 type sequence F description BINDING SITE FOR RESIDUE 9MG A 202 source : AC2 5) chain A residue 66 type sequence N description BINDING SITE FOR RESIDUE 9MG A 202 source : AC2 6) chain A residue 77 type sequence H description BINDING SITE FOR RESIDUE 9MG A 202 source : AC2 7) chain A residue 78 type sequence A description BINDING SITE FOR RESIDUE 9MG A 202 source : AC2 8) chain A residue 79 type sequence E description BINDING SITE FOR RESIDUE 9MG A 202 source : AC2 9) chain A residue 109 type sequence A description BINDING SITE FOR RESIDUE 9MG A 202 source : AC2 10) chain A residue 110 type sequence E description BINDING SITE FOR RESIDUE 9MG A 202 source : AC2 11) chain A residue 142 type sequence D description BINDING SITE FOR RESIDUE 9MG A 202 source : AC2 12) chain A residue 143 type sequence E description BINDING SITE FOR RESIDUE 9MG A 202 source : AC2 13) chain A residue 66 type sequence N description BINDING SITE FOR RESIDUE EDO A 203 source : AC3 14) chain A residue 141 type sequence F description BINDING SITE FOR RESIDUE EDO A 203 source : AC3 15) chain B residue 77 type sequence H description BINDING SITE FOR RESIDUE ZN B 201 source : AC4 16) chain B residue 112 type sequence C description BINDING SITE FOR RESIDUE ZN B 201 source : AC4 17) chain B residue 115 type sequence C description BINDING SITE FOR RESIDUE ZN B 201 source : AC4 18) chain B residue 8 type sequence G description BINDING SITE FOR RESIDUE EDO B 202 source : AC5 19) chain B residue 67 type sequence R description BINDING SITE FOR RESIDUE EDO B 202 source : AC5 20) chain B residue 71 type sequence G description BINDING SITE FOR RESIDUE EDO B 202 source : AC5 21) chain B residue 48 type sequence F description BINDING SITE FOR RESIDUE EDO B 203 source : AC6 22) chain B residue 79 type sequence E description BINDING SITE FOR RESIDUE EDO B 203 source : AC6 23) chain B residue 110 type sequence E description BINDING SITE FOR RESIDUE EDO B 203 source : AC6 24) chain B residue 143 type sequence E description BINDING SITE FOR RESIDUE EDO B 203 source : AC6 25) chain A residue 77-119 type prosite sequence HAEILALSLAQAKLDTHDLSADGLPACELVTSAEPCVMCF GAV description CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAEilALslaqakldthdlsadglpacelvtsae......PCvm......CfgaV source prosite : PS00903

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