eF-site ID 4lc2-A
PDB Code 4lc2
Chain A

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Title Crystal structure of the bromodomain of human BRPF1B
Classification DNA BINDING PROTEIN
Compound Peregrin
Source Homo sapiens (Human) (BRPF1_HUMAN)
Sequence A:  EMQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYL
DHIKKPMDFFTMKQNLEAYRYLNFDDFEEDFNLIVSNCLK
YNAKDTIFYRAAVRLREQGGAVLRQARRQAEKMG
Description


Functional site

1) chain A
residue 702
type
sequence S
description BINDING SITE FOR RESIDUE NO3 A 801
source : AC1

2) chain A
residue 705
type
sequence L
description BINDING SITE FOR RESIDUE NO3 A 801
source : AC1

3) chain A
residue 706
type
sequence K
description BINDING SITE FOR RESIDUE NO3 A 801
source : AC1

4) chain A
residue 715
type
sequence Y
description BINDING SITE FOR RESIDUE NO3 A 801
source : AC1

5) chain A
residue 722
type
sequence R
description BINDING SITE FOR RESIDUE NO3 A 801
source : AC1

6) chain A
residue 648
type
sequence D
description BINDING SITE FOR RESIDUE EDO A 802
source : AC2

7) chain A
residue 649
type
sequence T
description BINDING SITE FOR RESIDUE EDO A 802
source : AC2

8) chain A
residue 650
type
sequence G
description BINDING SITE FOR RESIDUE EDO A 802
source : AC2

9) chain A
residue 688
type
sequence L
description BINDING SITE FOR RESIDUE EDO A 802
source : AC2

10) chain A
residue 689
type
sequence N
description BINDING SITE FOR RESIDUE EDO A 802
source : AC2

11) chain A
residue 720
type
sequence R
description BINDING SITE FOR RESIDUE EDO A 802
source : AC2

12) chain A
residue 650-707
type prosite
sequence GNIFSEPVPLSEVPDYLDHIKKPMDFFTMKQNLEAYRYLN
FDDFEEDFNLIVSNCLKY
description BROMODOMAIN_1 Bromodomain signature. GniFsepvPlsevp..DYLdhIkkpMdfftMkqnleayr..Ylnfddfeedfnl.IvsNClkY
source prosite : PS00633


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