eF-site ID 4l7w-A PDB Code 4l7w Chain A click to enlarge Title Crystal structure mutant H77A of human HD domain-containing protein 2, Genomics Consortium (NESG) Target HR6723 Classification SIGNALING PROTEIN Compound HD domain-containing protein 2 Source Homo sapiens (Human) (HDDC2_HUMAN) Sequence A:  GARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHXYR XAVXAXVIKDDRLNKDRCVRLALVADXAECIVGDIAPADN IPKEEKHRREEEAXKQITQLLPEDLRKELYELWEEYETQS SAEAKFVKQLDQCEXILQASEYEDLEHKPGRLQDFYDSTA GKFNHPEIVQLVSELEAERSTNIAAAAS Description Functional site 1) chain A residue 81 type sequence E description BINDING SITE FOR RESIDUE MG A 301 source : AC1 2) chain A residue 86 type sequence D description BINDING SITE FOR RESIDUE MG A 301 source : AC1 3) chain A residue 32 type sequence R description BINDING SITE FOR RESIDUE MG A 302 source : AC2 4) chain A residue 86 type sequence D description BINDING SITE FOR RESIDUE MG A 302 source : AC2 5) chain A residue 32 type sequence R description BINDING SITE FOR RESIDUE MG A 303 source : AC3 6) chain A residue 78 type sequence D description BINDING SITE FOR RESIDUE MG A 303 source : AC3 7) chain A residue 81 type sequence E description BINDING SITE FOR RESIDUE MG A 303 source : AC3 8) chain A residue 86 type sequence D description BINDING SITE FOR RESIDUE MG A 303 source : AC3 9) chain A residue 81 type sequence E description BINDING SITE FOR RESIDUE MG A 304 source : AC4 10) chain A residue 86 type sequence D description BINDING SITE FOR RESIDUE MG A 304 source : AC4 11) chain A residue 87 type sequence I description BINDING SITE FOR RESIDUE MG A 304 source : AC4 12) chain A residue 98 type sequence K description BINDING SITE FOR RESIDUE MG A 304 source : AC4 13) chain A residue 78 type sequence D description BINDING SITE FOR RESIDUE MG A 305 source : AC5 14) chain A residue 81 type sequence E description BINDING SITE FOR RESIDUE MG A 305 source : AC5 15) chain A residue 49 type BINDING sequence H description BINDING => ECO:0007744|PDB:4DMB source Swiss-Prot : SWS_FT_FI1 16) chain A residue 77 type BINDING sequence A description BINDING => ECO:0007744|PDB:4DMB source Swiss-Prot : SWS_FT_FI1 17) chain A residue 78 type BINDING sequence D description BINDING => ECO:0007744|PDB:4DMB source Swiss-Prot : SWS_FT_FI1 18) chain A residue 143 type BINDING sequence D description BINDING => ECO:0007744|PDB:4DMB source Swiss-Prot : SWS_FT_FI1 19) chain A residue 81 type BINDING sequence E description BINDING => ECO:0007744|PDB:4L7W source Swiss-Prot : SWS_FT_FI2 20) chain A residue 87 type BINDING sequence I description BINDING => ECO:0007744|PDB:4L7W source Swiss-Prot : SWS_FT_FI2 21) chain A residue 86 type BINDING sequence D description BINDING => ECO:0007744|PDB:4L7W source Swiss-Prot : SWS_FT_FI2

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