eF-site ID 4l7e-A
PDB Code 4l7e
Chain A

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Title Three dimensional structure of mutant D78A of human HD domain-containing protein 2, Genomics Consortium (NESG) Target HR6723
Classification SIGNALING PROTEIN
Compound HD domain-containing protein 2
Source Homo sapiens (Human) (HDDC2_HUMAN)
Sequence A:  HGARSLLQFLRLVGQLKRVPRTGWVYRNVQRPESVSDHXY
RXAVXAXVIKDDRLNKDRCVRLALVHAXAECIVGDIAPAD
NIPKEEKHRREEEAXKQITQLLPEDLRKELYELWEEYETQ
SSAEAKFVKQLDQCEXILQASEYEDLEHKPGRLQDFYDST
AGKFNHPEIVQLVSELEAERSTNIAAA
Description


Functional site

1) chain A
residue 32
type
sequence R
description BINDING SITE FOR RESIDUE CL A 301
source : AC1

2) chain A
residue 49
type
sequence H
description BINDING SITE FOR RESIDUE CL A 301
source : AC1

3) chain A
residue 77
type
sequence H
description BINDING SITE FOR RESIDUE CL A 301
source : AC1

4) chain A
residue 143
type
sequence D
description BINDING SITE FOR RESIDUE CL A 301
source : AC1

5) chain A
residue 173
type
sequence G
description BINDING SITE FOR RESIDUE PEG A 302
source : AC2

6) chain A
residue 176
type
sequence N
description BINDING SITE FOR RESIDUE PEG A 302
source : AC2

7) chain A
residue 132
type
sequence S
description BINDING SITE FOR RESIDUE PEG A 303
source : AC3

8) chain A
residue 137
type
sequence K
description BINDING SITE FOR RESIDUE PEG A 303
source : AC3

9) chain A
residue 41
type
sequence Q
description BINDING SITE FOR RESIDUE PEG A 304
source : AC4

10) chain A
residue 158
type
sequence E
description BINDING SITE FOR RESIDUE PEG A 304
source : AC4

11) chain A
residue 160
type
sequence K
description BINDING SITE FOR RESIDUE PEG A 304
source : AC4

12) chain A
residue 163
type
sequence R
description BINDING SITE FOR RESIDUE PEG A 304
source : AC4

13) chain A
residue 82
type
sequence C
description BINDING SITE FOR RESIDUE PEG A 305
source : AC5

14) chain A
residue 83
type
sequence I
description BINDING SITE FOR RESIDUE PEG A 305
source : AC5

15) chain A
residue 85
type
sequence G
description BINDING SITE FOR RESIDUE PEG A 305
source : AC5

16) chain A
residue 166
type
sequence D
description BINDING SITE FOR RESIDUE PEG B 302
source : AC7

17) chain A
residue 90
type
sequence A
description BINDING SITE FOR RESIDUE PEG B 306
source : BC1

18) chain A
residue 92
type
sequence N
description BINDING SITE FOR RESIDUE PEG B 306
source : BC1

19) chain A
residue 49
type BINDING
sequence H
description BINDING => ECO:0007744|PDB:4DMB
source Swiss-Prot : SWS_FT_FI1

20) chain A
residue 77
type BINDING
sequence H
description BINDING => ECO:0007744|PDB:4DMB
source Swiss-Prot : SWS_FT_FI1

21) chain A
residue 78
type BINDING
sequence A
description BINDING => ECO:0007744|PDB:4DMB
source Swiss-Prot : SWS_FT_FI1

22) chain A
residue 143
type BINDING
sequence D
description BINDING => ECO:0007744|PDB:4DMB
source Swiss-Prot : SWS_FT_FI1

23) chain A
residue 81
type BINDING
sequence E
description BINDING => ECO:0007744|PDB:4L7W
source Swiss-Prot : SWS_FT_FI2

24) chain A
residue 86
type BINDING
sequence D
description BINDING => ECO:0007744|PDB:4L7W
source Swiss-Prot : SWS_FT_FI2

25) chain A
residue 87
type BINDING
sequence I
description BINDING => ECO:0007744|PDB:4L7W
source Swiss-Prot : SWS_FT_FI2


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