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eF-site ID
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4kud-ABCDEFGHIJ |
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PDB Code
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4kud |
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Chain
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A, B, C, D, E, F, G, H, I, J |
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click to enlarge
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Title
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Crystal structure of N-terminal acetylated Sir3 BAH domain D205N mutant in complex with yeast nucleosome core particle |
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Classification
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STRUCTURAL PROTEIN/TRANSCRIPTION/DNA |
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Compound
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Histone H3 |
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Source
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Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (SIR3_YEAST) |
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Sequence
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A: |
PHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIAQD
FKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAKRV
TIQKKDIKLARRLRGE
|
| B: |
AKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEV
RAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKRQG
RTLYGFGG
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| C: |
QSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAV
LEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELN
KLLGNVTIAQGGVLPNIHQNLLP
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| D: |
KETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERI
ATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSE
GTRAVTKYSSSTQ
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| E: |
KKPHRYKPGTVALREIRRFQKSTELLIRKLPFQRLVREIA
QDFKTDLRFQSSAIGALQESVEAYLVSLFEDTNLAAIHAK
RVTIQKKDIKLARRLRGE
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| F: |
GGAKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYE
EVRAVLKSFLESVIRDSVTYTEHAKRKTVTSLDVVYALKR
QGRTLYGFGG
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| G: |
SQSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTA
VLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDEL
NKLLGNVTIAQGGVLPNIHQNLLPK
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| H: |
RKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFER
IATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVS
EGTRAVTKYSSSTQ
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| I: |
ATCAATATCCACCTGCAGATTCTACCAAAAGTGTATTTGG
AAACTGCTCCATCAAAAGGCATGTTCAGCGGAATTCCGCT
GAACATGCCTTTTGATGGAGCAGTTTCCAAATACACTTTT
GGTAGAATCTGCAGGTGGATATTGAT
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| J: |
ATCAATATCCACCTGCAGATTCTACCAAAAGTGTATTTGG
AAACTGCTCCATCAAAAGGCATGTTCAGCGGAATTCCGCT
GAACATGCCTTTTGATGGAGCAGTTTCCAAATACACTTTT
GGTAGAATCTGCAGGTGGATATTGAT
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Description
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Functional site
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1)
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chain |
D |
| residue |
123 |
| type |
CROSSLNK |
| sequence |
K
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| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:10642555, ECO:0000269|PubMed:12535538, ECO:0000269|PubMed:12535539, ECO:0000269|PubMed:14660635, ECO:0000269|PubMed:15280549, ECO:0000269|PubMed:16432255
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| source |
Swiss-Prot : SWS_FT_FI11
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2)
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chain |
H |
| residue |
123 |
| type |
CROSSLNK |
| sequence |
K
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| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:10642555, ECO:0000269|PubMed:12535538, ECO:0000269|PubMed:12535539, ECO:0000269|PubMed:14660635, ECO:0000269|PubMed:15280549, ECO:0000269|PubMed:16432255
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| source |
Swiss-Prot : SWS_FT_FI11
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3)
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chain |
F |
| residue |
31 |
| type |
MOD_RES |
| sequence |
K
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| description |
N6-acetyllysine; alternate => ECO:0000269|PubMed:11545749, ECO:0000269|PubMed:15186774, ECO:0000269|PubMed:16598039, ECO:0000269|PubMed:19113941
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| source |
Swiss-Prot : SWS_FT_FI4
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4)
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chain |
F |
| residue |
77 |
| type |
MOD_RES |
| sequence |
K
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| description |
N6-acetyllysine; alternate => ECO:0000269|PubMed:11545749, ECO:0000269|PubMed:15186774, ECO:0000269|PubMed:16598039, ECO:0000269|PubMed:19113941
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| source |
Swiss-Prot : SWS_FT_FI4
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5)
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chain |
G |
| residue |
21 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine; alternate => ECO:0000269|PubMed:19113941
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| source |
Swiss-Prot : SWS_FT_FI5
|
|
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6)
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chain |
D |
| residue |
46 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-succinyllysine => ECO:0000269|PubMed:22389435
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| source |
Swiss-Prot : SWS_FT_FI8
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7)
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chain |
H |
| residue |
46 |
| type |
MOD_RES |
| sequence |
K
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| description |
N6-succinyllysine => ECO:0000269|PubMed:22389435
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| source |
Swiss-Prot : SWS_FT_FI8
|
|
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8)
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chain |
D |
| residue |
37 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6,N6-dimethyllysine => ECO:0000269|PubMed:19113941
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| source |
Swiss-Prot : SWS_FT_FI9
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9)
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chain |
H |
| residue |
37 |
| type |
MOD_RES |
| sequence |
K
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| description |
N6,N6-dimethyllysine => ECO:0000269|PubMed:19113941
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| source |
Swiss-Prot : SWS_FT_FI9
|
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10)
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chain |
D |
| residue |
95-117 |
| type |
prosite |
| sequence |
REIQTAVRLILPGELAKHAVSEG
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| description |
HISTONE_H2B Histone H2B signature. REIQTavRlILpGELaKHAVSEG
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| source |
prosite : PS00357
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11)
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chain |
A |
| residue |
66-74 |
| type |
prosite |
| sequence |
PFQRLVREI
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| description |
HISTONE_H3_2 Histone H3 signature 2. PFqRLVREI
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| source |
prosite : PS00959
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12)
|
chain |
C |
| residue |
22-28 |
| type |
prosite |
| sequence |
AGLTFPV
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| description |
HISTONE_H2A Histone H2A signature. AGLtFPV
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| source |
prosite : PS00046
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