eF-site ID 4k7s-C PDB Code 4k7s Chain C click to enlarge Title Crystal structure of Zn2-hUb (human ubiquitin) adduct from a solution 35 mM zinc acetate/1.3 mM hUb Classification LIGASE Compound ubiquitin Source Homo sapiens (Human) (UBC_HUMAN) Sequence C:  MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQ QRLIFAGKQLEDGRTLSDYNIQKESTLHLVLR Description Functional site 1) chain C residue 18 type sequence E description BINDING SITE FOR RESIDUE EDO A 103 source : AC3 2) chain C residue 51 type sequence E description BINDING SITE FOR RESIDUE ZN B 102 source : AC5 3) chain C residue 1 type sequence M description BINDING SITE FOR RESIDUE ZN C 101 source : AC7 4) chain C residue 16 type sequence E description BINDING SITE FOR RESIDUE ZN C 101 source : AC7 5) chain C residue 18 type sequence E description BINDING SITE FOR RESIDUE ZN C 102 source : AC8 6) chain C residue 18 type sequence E description BINDING SITE FOR RESIDUE ACT C 103 source : AC9 7) chain C residue 7 type sequence T description BINDING SITE FOR RESIDUE EDO C 104 source : BC1 8) chain C residue 8 type sequence L description BINDING SITE FOR RESIDUE EDO C 104 source : BC1 9) chain C residue 69 type sequence L description BINDING SITE FOR RESIDUE EDO C 104 source : BC1 10) chain C residue 54 type SITE sequence R description Interacts with activating enzyme source Swiss-Prot : SWS_FT_FI1 11) chain C residue 72 type SITE sequence R description Interacts with activating enzyme source Swiss-Prot : SWS_FT_FI1 12) chain C residue 68 type SITE sequence H description Essential for function source Swiss-Prot : SWS_FT_FI2 13) chain C residue 65 type MOD_RES sequence S description Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291 source Swiss-Prot : SWS_FT_FI3 14) chain C residue 63 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106 source Swiss-Prot : SWS_FT_FI12 15) chain C residue 66 type MOD_RES sequence T description (Microbial infection) ADP-ribosylthreonine => ECO:0000269|PubMed:32330457 source Swiss-Prot : SWS_FT_FI4 16) chain C residue 6 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603 source Swiss-Prot : SWS_FT_FI6 17) chain C residue 29 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127 source Swiss-Prot : SWS_FT_FI10 18) chain C residue 11 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144 source Swiss-Prot : SWS_FT_FI8 19) chain C residue 48 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144 source Swiss-Prot : SWS_FT_FI8 20) chain C residue 27 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860 source Swiss-Prot : SWS_FT_FI9 21) chain C residue 33 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577 source Swiss-Prot : SWS_FT_FI11

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