eF-site ID 4jsu-V PDB Code 4jsu Chain V click to enlarge Title Yeast 20S proteasome in complex with the dimerized linear mimetic of TMC-95A - yCP:3a Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome subunit alpha type-2 Source ORGANISM_COMMON: yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence V:  TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPK IWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSAL QMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ AGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQ KSYKFPRGTTAVLKESIVNICD Description Functional site 1) chain V residue 1 type sequence T description BINDING SITE FOR CHAIN f OF TMC-95A MIMIC LIGAND YCP:3A source : AC6 2) chain V residue 20 type sequence S description BINDING SITE FOR CHAIN f OF TMC-95A MIMIC LIGAND YCP:3A source : AC6 3) chain V residue 21 type sequence T description BINDING SITE FOR CHAIN f OF TMC-95A MIMIC LIGAND YCP:3A source : AC6 4) chain V residue 31 type sequence C description BINDING SITE FOR CHAIN f OF TMC-95A MIMIC LIGAND YCP:3A source : AC6 5) chain V residue 47 type sequence G description BINDING SITE FOR CHAIN f OF TMC-95A MIMIC LIGAND YCP:3A source : AC6 6) chain V residue 48 type sequence T description BINDING SITE FOR CHAIN f OF TMC-95A MIMIC LIGAND YCP:3A source : AC6 7) chain V residue 49 type sequence A description BINDING SITE FOR CHAIN f OF TMC-95A MIMIC LIGAND YCP:3A source : AC6 8) chain V residue 1 type catalytic sequence T description 177 source MCSA : MCSA2 9) chain V residue 17 type catalytic sequence D description 177 source MCSA : MCSA2 10) chain V residue 19 type catalytic sequence R description 177 source MCSA : MCSA2 11) chain V residue 33 type catalytic sequence K description 177 source MCSA : MCSA2 12) chain V residue 47 type catalytic sequence G description 177 source MCSA : MCSA2 13) chain V residue 129 type catalytic sequence S description 177 source MCSA : MCSA2 14) chain V residue 166 type catalytic sequence D description 177 source MCSA : MCSA2 15) chain V residue 169 type catalytic sequence S description 177 source MCSA : MCSA2

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