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eF-site ID
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4jsq-H |
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PDB Code
|
4jsq |
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Chain
|
H |
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click to enlarge
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Title
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Yeast 20S proteasome in complex with the dimerized linear mimetic of TMC-95A - yCP:4e |
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Classification
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HYDROLASE/HYDROLASE INHIBITOR |
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Compound
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Proteasome subunit alpha type-2 |
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Source
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ORGANISM_COMMON: yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
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H: |
TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPK
IWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSAL
QMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD
VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ
AGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQ
KSYKFPRGTTAVLKESIVNICD
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Description
|
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Functional site
|
|
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1)
|
chain |
H |
| residue |
1 |
| type |
catalytic |
| sequence |
T
|
| description |
177
|
| source |
MCSA : MCSA1
|
|
|
2)
|
chain |
H |
| residue |
17 |
| type |
catalytic |
| sequence |
D
|
| description |
177
|
| source |
MCSA : MCSA1
|
|
|
3)
|
chain |
H |
| residue |
19 |
| type |
catalytic |
| sequence |
R
|
| description |
177
|
| source |
MCSA : MCSA1
|
|
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4)
|
chain |
H |
| residue |
33 |
| type |
catalytic |
| sequence |
K
|
| description |
177
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
H |
| residue |
47 |
| type |
catalytic |
| sequence |
G
|
| description |
177
|
| source |
MCSA : MCSA1
|
|
|
6)
|
chain |
H |
| residue |
129 |
| type |
catalytic |
| sequence |
S
|
| description |
177
|
| source |
MCSA : MCSA1
|
|
|
7)
|
chain |
H |
| residue |
166 |
| type |
catalytic |
| sequence |
D
|
| description |
177
|
| source |
MCSA : MCSA1
|
|
|
8)
|
chain |
H |
| residue |
169 |
| type |
catalytic |
| sequence |
S
|
| description |
177
|
| source |
MCSA : MCSA1
|
|
|
9)
|
chain |
H |
| residue |
4-51 |
| type |
prosite |
| sequence |
VGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWC
AGAGTAAD
|
| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGVkFnnGVVIAADtrstqgpivadknca.KlhrispkiwcagaGtaAD
|
| source |
prosite : PS00854
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