eF-site ID 4jmh-AB PDB Code 4jmh Chain A, B click to enlarge Title Crystal structure of synthetic protein in complex with double pY peptide Classification DE NOVO PROTEIN Compound Clamp Shc1_pY239/240 Source Homo sapiens (Human) (4JMH) Sequence A:  GSVKFNSLDELVDYHRSTSVSRNQQIFLRDIGGGGHPWYK GKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFG NDVQHFKVLRDGAGKYFLWVGGSGGSVSSVPTKLEVVAAT PTSLLISWDAIWYPYYVSYYRITYGETGGNSPVQEFTVPG YSSTATISGLSPGVDYTITIYAKYHRAKYYSSPISINYRT B:  HQXXNDFP Description Functional site 1) chain A residue 21 type sequence S description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 2) chain A residue 22 type sequence R description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 3) chain A residue 23 type sequence N description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 4) chain A residue 47 type sequence R description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 5) chain A residue 66 type sequence R description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 6) chain A residue 68 type sequence S description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 7) chain A residue 69 type sequence E description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 8) chain A residue 70 type sequence S description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 9) chain A residue 76 type sequence S description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 10) chain A residue 86 type sequence Q description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 11) chain A residue 87 type sequence H description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 12) chain A residue 88 type sequence F description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 13) chain A residue 89 type sequence K description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 14) chain A residue 100 type sequence L description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 15) chain A residue 101 type sequence W description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 16) chain A residue 102 type sequence V description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 17) chain A residue 137 type sequence Y description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 18) chain A residue 138 type sequence Y description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 19) chain A residue 139 type sequence V description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 20) chain A residue 140 type sequence S description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 21) chain A residue 187 type sequence H description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 22) chain A residue 188 type sequence R description BINDING SITE FOR CHAIN B OF SHC-TRANSFORMING PROTEIN 1 source : AC1 23) chain B residue 239 type MOD_RES sequence X description Phosphotyrosine => ECO:0000269|PubMed:8939605, ECO:0000269|PubMed:9121430, ECO:0000269|PubMed:9566877 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 240 type MOD_RES sequence X description Phosphotyrosine => ECO:0000269|PubMed:8939605, ECO:0000269|PubMed:9121430, ECO:0000269|PubMed:9566877 source Swiss-Prot : SWS_FT_FI1 25) chain A residue 147-154 type prosite sequence GETGGNSP description ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GETGGNSP source prosite : PS00687

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