|
|
eF-site ID
|
4jgh-D |
|
PDB Code
|
4jgh |
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Chain
|
D |
|
click to enlarge
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Title
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Structure of the SOCS2-Elongin BC complex bound to an N-terminal fragment of Cullin5 |
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Classification
|
LIGASE |
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Compound
|
Suppressor of cytokine signaling 2 |
|
Source
|
Homo sapiens (Human) (CUL5_HUMAN) |
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Sequence
|
D: |
KGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHA
VCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTAL
LKAYIVEWRKFFTQCDILPKPFCQLEITLNVEDSIVRKLM
LDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIG
VRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAP
SYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVE
ALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSL
MDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEK
YREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVND
ATIFKLEV
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Description
|
|
Functional site
|
|
|
1)
|
chain |
D |
| residue |
34 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:23186163
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
D |
| residue |
210 |
| type |
MOD_RES |
| sequence |
T
|
| description |
Phosphothreonine => ECO:0007744|PubMed:18669648
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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|
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