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Title
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Structure of the SOCS2-Elongin BC complex bound to an N-terminal fragment of Cullin5 |
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Classification
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LIGASE |
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Compound
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Suppressor of cytokine signaling 2 |
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Source
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Homo sapiens (Human) (CUL5_HUMAN) |
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Sequence
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A: |
HMDPEFQAARLAKALRELGQTGWYWGSMTVNEAKEKLKEA
PEGTFLIRDSSHSDYLLTISVKTSAGPTNLRIEYQDGKFR
LDSIICVKSKLKQFDSVVHLIDYYVQMCKDGTVHLYLTKP
LYTSAPSLQHLCRLTINKCTGAIWGLPLPTRLKDYLEEYK
FQV
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| B: |
MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPE
EQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFR
ADDTFEALRIEPFSSPPELPDVMK
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| C: |
MYVKLISSDGHEFIVKREHALTSGTIKAMLSGPGQFAENE
TNEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIA
PEIPLELLMAANFLDC
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| D: |
KGSLQFEDKWDFMRPIVLKLLRQESVTKQQWFDLFSDVHA
VCLWDDKGPAKIHQALKEDILEFIKQAQARVLSHQDDTAL
LKAYIVEWRKFFTQCDILPKPFCQLEITLNVEDSIVRKLM
LDTWNESIFSNIKNRLQDSAMKLVHAERLGEAFDSQLVIG
VRESYVNLCSNPEDKLQIYRDNFEKAYLDSTERFYRTQAP
SYLQQNGVQNYMKYADAKLKEEEKRALRYLETRRECNSVE
ALMECCVNALVTSFKETILAECQGMIKRNETEKLHLMFSL
MDKVPNGIEPMLKDLEEHIISAGLADMVAAAETITTDSEK
YREQLDTLFNRFSKLVKEAFQDDPRFLTARDKAYKAVVND
ATIFKLEV
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Description
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