|
|
eF-site ID
|
4jeq-J |
|
PDB Code
|
4jeq |
|
Chain
|
J |
|
click to enlarge
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|
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Title
|
Different Contribution of Conserved Amino Acids to the Global Properties of Homologous Enzymes |
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Classification
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ISOMERASE |
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Compound
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TRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL |
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Source
|
Trypanosoma brucei brucei (TPIS_TRYBB) |
|
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Sequence
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J: |
MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCV
VASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFTGEVSL
PILKDFGVNWIVLGHSERRAYYGDTNEIVADKVAAAVASG
FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWA
KVVIAYEPVWAIGGKVATPQQAQEAHALIRSWVSSKIGAD
VAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE
FVDIIKATQ
|
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Description
|
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Functional site
|
|
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1)
|
chain |
J |
| residue |
95 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Electrophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
J |
| residue |
167 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
J |
| residue |
11 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
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4)
|
chain |
J |
| residue |
13 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|