|
|
eF-site ID
|
4jeq-I |
|
PDB Code
|
4jeq |
|
Chain
|
I |
|
click to enlarge
|
|
|
Title
|
Different Contribution of Conserved Amino Acids to the Global Properties of Homologous Enzymes |
|
Classification
|
ISOMERASE |
|
Compound
|
TRIOSEPHOSPHATE ISOMERASE, GLYCOSOMAL |
|
Source
|
Trypanosoma brucei brucei (TPIS_TRYBB) |
|
|
Sequence
|
I: |
MSKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCV
VASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFTGEVSL
PILKDFGVNWIVLGHSERRAYYGDTNEIVADKVAAAVASG
FMVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWA
KVVIAYEPVWAGKVATPQQAQEAHALIRSWVSSKIGADVA
GELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPEFV
DIIKATQ
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
I |
| residue |
193 |
| type |
|
| sequence |
W
|
| description |
BINDING SITE FOR RESIDUE SO4 D 301
|
| source |
: AC6
|
|
|
2)
|
chain |
I |
| residue |
11 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
3)
|
chain |
I |
| residue |
13 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
I |
| residue |
95 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Electrophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
I |
| residue |
167 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|