eF-site ID 4jdv-ABHL PDB Code 4jdv Chain A, B, H, L click to enlarge Title Crystal structure of germ-line precursor of NIH45-46 Fab Classification IMMUNE SYSTEM Compound Fab heavy chain Source (4JDV) Sequence A:  VQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAP GQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYM ELSRLRSDDTAVYYCARGKYCTARDYYNWDFQHWGQGTLV TVSSASTKGPSVFPLAPSSKGTAALGCLVKDYFPEPVTVS WNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQT YICNVNHKPSNTKVDKRVEPKSCDKTH B:  IVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKPG QAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEPE DFAVYYCQQYEFFGQGTKLEIKRTVAAPSVFIFPPSDEQL KSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTE QDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPV TKSFNRGE H:  VQLVQSGAEVKKPGASVKVSCKASGYTFTGYYMHWVRQAP GQGLEWMGWINPNSGGTNYAQKFQGRVTMTRDTSISTAYM ELSRLRSDDTAVYYCARGKYCTARDYYNWDFQHWGQGTLV TVSSASTKGPSVFPLAPSTAALGCLVKDYFPEPVTVSWNS GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLQTYICNV NHKPSNTKVDKRVEP L:  EIVLTQSPATLSLSPGERATLSCRASQSVSSYLAWYQQKP GQAPRLLIYDASNRATGIPARFSGSGSGTDFTLTISSLEP EDFAVYYCQQYEFFGQGTKLEIKRTVAAPSVFIFPPSDEQ LKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVT EQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSP VTKSFNRGE Description Functional site 1) chain A residue 82 type sequence L description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 2) chain A residue 83 type sequence R description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 3) chain H residue 54 type sequence S description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 4) chain H residue 56 type sequence G description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 5) chain A residue 7 type sequence S description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 6) chain A residue 8 type sequence G description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 7) chain L residue 18 type sequence R description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 8) chain L residue 20 type sequence T description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 9) chain A residue 170 type sequence F description BINDING SITE FOR RESIDUE GOL A 303 source : AC3 10) chain A residue 171 type sequence P description BINDING SITE FOR RESIDUE GOL A 303 source : AC3 11) chain A residue 181 type sequence S description BINDING SITE FOR RESIDUE GOL A 303 source : AC3 12) chain A residue 182 type sequence L description BINDING SITE FOR RESIDUE GOL A 303 source : AC3 13) chain A residue 183 type sequence S description BINDING SITE FOR RESIDUE GOL A 303 source : AC3 14) chain B residue 172 type sequence S description BINDING SITE FOR RESIDUE GOL A 303 source : AC3 15) chain B residue 173 type sequence S description BINDING SITE FOR RESIDUE GOL A 303 source : AC3 16) chain B residue 174 type sequence T description BINDING SITE FOR RESIDUE GOL A 303 source : AC3 17) chain A residue 152 type sequence E description BINDING SITE FOR RESIDUE 144 A 304 source : AC4 18) chain A residue 153 type sequence P description BINDING SITE FOR RESIDUE 144 A 304 source : AC4 19) chain A residue 154 type sequence V description BINDING SITE FOR RESIDUE 144 A 304 source : AC4 20) chain A residue 170 type sequence F description BINDING SITE FOR RESIDUE 144 A 304 source : AC4 21) chain A residue 172 type sequence A description BINDING SITE FOR RESIDUE 144 A 304 source : AC4 22) chain A residue 182 type sequence L description BINDING SITE FOR RESIDUE 144 A 304 source : AC4 23) chain B residue 186 type sequence K description BINDING SITE FOR RESIDUE SO4 B 301 source : AC5 24) chain B residue 207 type sequence R description BINDING SITE FOR RESIDUE SO4 B 301 source : AC5 25) chain A residue 168 type sequence H description BINDING SITE FOR RESIDUE GOL B 302 source : AC6 26) chain B residue 161 type sequence E description BINDING SITE FOR RESIDUE GOL B 302 source : AC6 27) chain B residue 162 type sequence Q description BINDING SITE FOR RESIDUE GOL B 302 source : AC6 28) chain B residue 163 type sequence D description BINDING SITE FOR RESIDUE GOL B 302 source : AC6 29) chain H residue 152 type sequence E description BINDING SITE FOR RESIDUE 144 H 301 source : AC7 30) chain H residue 153 type sequence P description BINDING SITE FOR RESIDUE 144 H 301 source : AC7 31) chain H residue 154 type sequence V description BINDING SITE FOR RESIDUE 144 H 301 source : AC7 32) chain H residue 170 type sequence F description BINDING SITE FOR RESIDUE 144 H 301 source : AC7 33) chain H residue 172 type sequence A description BINDING SITE FOR RESIDUE 144 H 301 source : AC7 34) chain H residue 182 type sequence L description BINDING SITE FOR RESIDUE 144 H 301 source : AC7 35) chain A residue 61 type sequence Q description BINDING SITE FOR RESIDUE 1PE H 302 source : AC8 36) chain H residue 50 type sequence W description BINDING SITE FOR RESIDUE 1PE H 302 source : AC8 37) chain H residue 58 type sequence N description BINDING SITE FOR RESIDUE 1PE H 302 source : AC8 38) chain H residue 102 type sequence W description BINDING SITE FOR RESIDUE 1PE H 302 source : AC8 39) chain L residue 91 type sequence Y description BINDING SITE FOR RESIDUE 1PE H 302 source : AC8 40) chain L residue 92 type sequence E description BINDING SITE FOR RESIDUE 1PE H 302 source : AC8 41) chain H residue 62 type sequence K description BINDING SITE FOR RESIDUE SO4 L 301 source : AC9 42) chain H residue 64 type sequence Q description BINDING SITE FOR RESIDUE SO4 L 301 source : AC9 43) chain L residue 186 type sequence K description BINDING SITE FOR RESIDUE SO4 L 301 source : AC9 44) chain L residue 207 type sequence R description BINDING SITE FOR RESIDUE SO4 L 301 source : AC9 45) chain A residue 138 type sequence G description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 46) chain A residue 139 type sequence T description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 47) chain A residue 188 type sequence V description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 48) chain A residue 189 type sequence P description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 49) chain L residue 37 type sequence Q description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 50) chain L residue 39 type sequence K description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 51) chain L residue 45 type sequence R description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 52) chain L residue 59 type sequence P description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 53) chain L residue 60 type sequence A description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 54) chain L residue 61 type sequence R description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 55) chain L residue 81 type sequence E description BINDING SITE FOR RESIDUE 1PE L 302 source : BC1 56) chain B residue 188-194 type prosite sequence YACEVTH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290 57) chain A residue 198-204 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH source prosite : PS00290

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