|
|
eF-site ID
|
4iuz-A |
|
PDB Code
|
4iuz |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
High resolution crystal structure of racemic ester insulin |
|
Classification
|
HORMONE PRECURSOR |
|
Compound
|
Insulin A chain |
|
Source
|
Homo sapiens (Human) (INS_HUMAN) |
|
|
Sequence
|
A: |
GIVEQCCTSICSLYQLENYCN
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
17 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE PEG B 101
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
20 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE PEG B 101
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
15 |
| type |
|
| sequence |
Q
|
| description |
BINDING SITE FOR RESIDUE GOL B 102
|
| source |
: AC2
|
|
|
4)
|
chain |
A |
| residue |
7 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE PEG B 103
|
| source |
: AC3
|
|
|
5)
|
chain |
A |
| residue |
6-20 |
| type |
prosite |
| sequence |
CCTSICSLYQLENYC
|
| description |
INSULIN Insulin family signature. CCTSiCSlyqLenyC
|
| source |
prosite : PS00262
|
|
|
|