eF-site ID 4itx-B PDB Code 4itx Chain B click to enlarge Title P113S mutant of E. coli Cystathionine beta-lyase MetC inhibited by reaction with L-Ala-P Classification LYASE Compound Cystathionine beta-lyase MetC Source Escherichia coli (strain K12) (METC_ECOLI) Sequence B:  KKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKK HATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLF PCGAAAVANSILAFIEQGDHVLMTNTAYESSQDFCSKILS KLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEV HDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDV SIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLMGQM VDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQV ARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNNEE LANYLDNFSLFSMAYSWGGYESLILANQPEHIAAIRPQGE IDFSGTLIRLHIGLEDVDDLIADLDAGFARIV Description Functional site 1) chain B residue 333 type sequence L description BINDING SITE FOR RESIDUE CA A 402 source : AC2 2) chain B residue 344 type sequence E description BINDING SITE FOR RESIDUE CA A 402 source : AC2 3) chain B residue 56 type sequence Y description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 4) chain B residue 58 type sequence R description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 5) chain B residue 85 type sequence C description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 6) chain B residue 86 type sequence G description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 7) chain B residue 87 type sequence A description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 8) chain B residue 111 type sequence Y description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 9) chain B residue 154 type sequence E description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 10) chain B residue 185 type sequence D description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 11) chain B residue 207 type sequence A description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 12) chain B residue 209 type sequence T description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 13) chain B residue 210 type sequence K description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 14) chain B residue 219 type sequence M description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 15) chain B residue 338 type sequence Y description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 16) chain B residue 339 type sequence S description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 17) chain B residue 340 type sequence W description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 18) chain B residue 372 type sequence R description BINDING SITE FOR RESIDUE IN5 B 401 source : AC3 19) chain B residue 12 type sequence N description BINDING SITE FOR RESIDUE CA B 402 source : AC4 20) chain B residue 58 type catalytic sequence R description 449 source MCSA : MCSA2 21) chain B residue 111 type catalytic sequence Y description 449 source MCSA : MCSA2 22) chain B residue 185 type catalytic sequence D description 449 source MCSA : MCSA2 23) chain B residue 210 type catalytic sequence K description 449 source MCSA : MCSA2 24) chain B residue 210 type MOD_RES sequence K description N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:3307782, ECO:0000269|PubMed:8831789 source Swiss-Prot : SWS_FT_FI1

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