|
|
eF-site ID
|
4inu-Z |
|
PDB Code
|
4inu |
|
Chain
|
Z |
|
click to enlarge
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Title
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Yeast 20S proteasome in complex with the vinyl sulfone LU112 |
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Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
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Compound
|
Proteasome component Y7 |
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Source
|
ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
|
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Sequence
|
Z: |
QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYE
PKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHN
DKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKG
AVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQY
EPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGD
GLEILIVTKDGVRKEFYELKRD
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Description
|
|
Functional site
|
|
|
1)
|
chain |
Z |
| residue |
108 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE 1G6 Y 301
|
| source |
: AC4
|
|
|
2)
|
chain |
Z |
| residue |
125 |
| type |
|
| sequence |
F
|
| description |
BINDING SITE FOR RESIDUE 1G6 Y 301
|
| source |
: AC4
|
|
|
3)
|
chain |
Z |
| residue |
126 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE 1G6 Y 301
|
| source |
: AC4
|
|
|
4)
|
chain |
Z |
| residue |
127 |
| type |
|
| sequence |
P
|
| description |
BINDING SITE FOR RESIDUE 1G6 Y 301
|
| source |
: AC4
|
|
|
5)
|
chain |
Z |
| residue |
130 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE 1G6 Y 301
|
| source |
: AC4
|
|
|
6)
|
chain |
Z |
| residue |
137 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE 1G6 Y 301
|
| source |
: AC4
|
|
|
|