|
|
eF-site ID
|
4inu-W |
|
PDB Code
|
4inu |
|
Chain
|
W |
|
click to enlarge
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|
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Title
|
Yeast 20S proteasome in complex with the vinyl sulfone LU112 |
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Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
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Compound
|
Proteasome component Y7 |
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Source
|
ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
|
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Sequence
|
W: |
SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFE
KIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERA
IEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFI
AGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPE
DLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLK
MRQD
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Description
|
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Functional site
|
|
|
1)
|
chain |
W |
| residue |
123 |
| type |
|
| sequence |
F
|
| description |
BINDING SITE FOR RESIDUE 1G6 V 301
|
| source |
: AC3
|
|
|
2)
|
chain |
W |
| residue |
124 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE 1G6 V 301
|
| source |
: AC3
|
|
|
3)
|
chain |
W |
| residue |
126 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE 1G6 V 301
|
| source |
: AC3
|
|
|
4)
|
chain |
W |
| residue |
130 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE 1G6 V 301
|
| source |
: AC3
|
|
|
5)
|
chain |
W |
| residue |
69 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|