eF-site ID 4inu-V PDB Code 4inu Chain V click to enlarge Title Yeast 20S proteasome in complex with the vinyl sulfone LU112 Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome component Y7 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence V:  TTIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPK IWCAGAGTAADTEAVTQLIGSNIELHSLYTSREPRVVSAL QMLKQHLFKYQGHIGAYLIVAGVDPTGSHLFSIHAHGSTD VGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQ AGIWNDLGSGSNVDVCVMEIGKDAEYLRNYLTPNVREEKQ KSYKFPRGTTAVLKESIVNICD Description Functional site 1) chain V residue 1 type sequence T description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 2) chain V residue 20 type sequence S description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 3) chain V residue 21 type sequence T description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 4) chain V residue 22 type sequence Q description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 5) chain V residue 31 type sequence C description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 6) chain V residue 32 type sequence A description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 7) chain V residue 33 type sequence K description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 8) chain V residue 45 type sequence G description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 9) chain V residue 46 type sequence A description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 10) chain V residue 47 type sequence G description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 11) chain V residue 48 type sequence T description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 12) chain V residue 49 type sequence A description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 13) chain V residue 53 type sequence E description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 14) chain V residue 128 type sequence G description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 15) chain V residue 129 type sequence S description BINDING SITE FOR RESIDUE 1G6 V 301 source : AC3 16) chain V residue 1 type catalytic sequence T description 177 source MCSA : MCSA2 17) chain V residue 17 type catalytic sequence D description 177 source MCSA : MCSA2 18) chain V residue 19 type catalytic sequence R description 177 source MCSA : MCSA2 19) chain V residue 33 type catalytic sequence K description 177 source MCSA : MCSA2 20) chain V residue 47 type catalytic sequence G description 177 source MCSA : MCSA2 21) chain V residue 129 type catalytic sequence S description 177 source MCSA : MCSA2 22) chain V residue 166 type catalytic sequence D description 177 source MCSA : MCSA2 23) chain V residue 169 type catalytic sequence S description 177 source MCSA : MCSA2

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