|
|
eF-site ID
|
4int-Z |
|
PDB Code
|
4int |
|
Chain
|
Z |
|
click to enlarge
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Title
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Yeast 20S proteasome in complex with the vinyl sulfone LU122 |
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Classification
|
HYDROLASE/HYDROLASE INHIBITOR |
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Compound
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Proteasome component Y7 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
|
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Sequence
|
Z: |
QFNPYGDNGGTILGIAGEDFAVLAGDTRNITDYSINSRYE
PKVFDCGDNIVMSANGFAADGDALVKRFKNSVKWYHFDHN
DKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKG
AVYSFDPVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQY
EPGTNGKVKKPLKYLSVEEVIKLVRDSFTSATERHIQVGD
GLEILIVTKDGVRKEFYELKRD
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Description
|
|
Functional site
|
|
|
1)
|
chain |
Z |
| residue |
126 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE 1G5 Y 301
|
| source |
: AC4
|
|
|
2)
|
chain |
Z |
| residue |
127 |
| type |
|
| sequence |
P
|
| description |
BINDING SITE FOR RESIDUE 1G5 Y 301
|
| source |
: AC4
|
|
|
3)
|
chain |
Z |
| residue |
128 |
| type |
|
| sequence |
V
|
| description |
BINDING SITE FOR RESIDUE 1G5 Y 301
|
| source |
: AC4
|
|
|
4)
|
chain |
Z |
| residue |
130 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE 1G5 Y 301
|
| source |
: AC4
|
|
|
5)
|
chain |
Z |
| residue |
132 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE 1G5 Y 301
|
| source |
: AC4
|
|
|
|