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eF-site ID
|
4int-I |
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PDB Code
|
4int |
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Chain
|
I |
|
click to enlarge
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Title
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Yeast 20S proteasome in complex with the vinyl sulfone LU122 |
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Classification
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HYDROLASE/HYDROLASE INHIBITOR |
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Compound
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Proteasome component Y7 |
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Source
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ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; |
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Sequence
|
I: |
SDPSSINGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFE
KIFHYGHVFLGITGLATDVTTLNEMFRYKTNLYKLKEERA
IEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFI
AGFDLIGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPE
DLFETISQALLNAADRDALSGWGAVVYIIKKDEVVKRYLK
MRQD
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Description
|
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Functional site
|
|
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1)
|
chain |
I |
| residue |
124 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE 1G5 H 301
|
| source |
: AC1
|
|
|
2)
|
chain |
I |
| residue |
125 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE 1G5 H 301
|
| source |
: AC1
|
|
|
3)
|
chain |
I |
| residue |
128 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE 1G5 H 301
|
| source |
: AC1
|
|
|
4)
|
chain |
I |
| residue |
12-58 |
| type |
prosite |
| sequence |
VAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLG
ITGLATD
|
| description |
PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGVkFnnGVVIAADtrstqgpivadknca.KlhrispkiwcagaGtaAD
|
| source |
prosite : PS00854
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