|
|
eF-site ID
|
4iak-S |
|
PDB Code
|
4iak |
|
Chain
|
S |
|
click to enlarge
|
|
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Title
|
Low temperature X-ray structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20 |
|
Classification
|
Transferase/Peptide |
|
Compound
|
cAMP-dependent protein kinase catalytic subunit alpha |
|
Source
|
Mus musculus (Mouse) (4IAK) |
|
|
Sequence
|
S: |
TTYADFIASGRTGRRAXIHD
|
|
|
Description
|
(1) |
cAMP-dependent protein kinase catalytic subunit alpha (E.C.2.7.11.11), phosphorylated pseudo-substrate peptide pSP20
|
|
Functional site
|
|
|
1)
|
chain |
S |
| residue |
621 |
| type |
|
| sequence |
X
|
| description |
BINDING SITE FOR RESIDUE SR A 401
|
| source |
: AC1
|
|
|
2)
|
chain |
S |
| residue |
618 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE ADP A 403
|
| source |
: AC3
|
|
|
3)
|
chain |
S |
| residue |
621 |
| type |
|
| sequence |
X
|
| description |
BINDING SITE FOR RESIDUE ADP A 403
|
| source |
: AC3
|
|
|
4)
|
chain |
S |
| residue |
615 |
| type |
SITE |
| sequence |
R
|
| description |
Important for inhibition => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
S |
| residue |
618 |
| type |
SITE |
| sequence |
R
|
| description |
Important for inhibition => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
S |
| residue |
619 |
| type |
SITE |
| sequence |
R
|
| description |
Important for inhibition => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|