eF-site ID 4i7b-C PDB Code 4i7b Chain C click to enlarge Title Siah1 bound to synthetic peptide (ACE)KLRPV(ABA)MVRPTVR Classification LIGASE/LIGASE INHIBITOR Compound E3 ubiquitin-protein ligase SIAH1 Source Homo sapiens (Human) (PHYL_DROME) Sequence C:  VLFPCKYASSGCEITLPHTEKADHEELCEFRPYSCPCPGA SCKWQGSLDAVMPHLMHQHKSITTLQGEDIVFLATDINLP GAVDWVMMQSCFGFHFMLVLEKQEDGHQQFFAIVQLIGTR KQAENFAYRLELNGHRRRLTWEATPRSIHEGIATAIMNSD CLVFDTSIAQLFAENGNLGINVTISMC Description Functional site 1) chain C residue 128 type sequence C description BINDING SITE FOR RESIDUE ZN C 601 source : AC3 2) chain C residue 135 type sequence C description BINDING SITE FOR RESIDUE ZN C 601 source : AC3 3) chain C residue 147 type sequence H description BINDING SITE FOR RESIDUE ZN C 601 source : AC3 4) chain C residue 152 type sequence H description BINDING SITE FOR RESIDUE ZN C 601 source : AC3 5) chain C residue 98 type sequence C description BINDING SITE FOR RESIDUE ZN C 602 source : AC4 6) chain C residue 105 type sequence C description BINDING SITE FOR RESIDUE ZN C 602 source : AC4 7) chain C residue 117 type sequence H description BINDING SITE FOR RESIDUE ZN C 602 source : AC4 8) chain C residue 121 type sequence C description BINDING SITE FOR RESIDUE ZN C 602 source : AC4 9) chain C residue 268 type sequence A description BINDING SITE FOR CHAIN B OF PROTEIN PHYLLOPOD source : AC5 10) chain C residue 269 type sequence E description BINDING SITE FOR CHAIN B OF PROTEIN PHYLLOPOD source : AC5 11) chain C residue 156 type sequence T description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 12) chain C residue 158 type sequence L description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 13) chain C residue 162 type sequence D description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 14) chain C residue 163 type sequence I description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 15) chain C residue 164 type sequence V description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 16) chain C residue 165 type sequence F description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 17) chain C residue 166 type sequence L description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 18) chain C residue 168 type sequence T description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 19) chain C residue 176 type sequence V description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 20) chain C residue 177 type sequence D description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 21) chain C residue 178 type sequence W description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 22) chain C residue 179 type sequence V description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 23) chain C residue 180 type sequence M description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 24) chain C residue 276 type sequence N description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 25) chain C residue 282 type sequence C description BINDING SITE FOR CHAIN D OF PROTEIN PHYLLOPOD source : AC6 26) chain C residue 98 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28546513, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI2 27) chain C residue 105 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28546513, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI2 28) chain C residue 117 type BINDING sequence H description BINDING => ECO:0000269|PubMed:28546513, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI2 29) chain C residue 121 type BINDING sequence C description BINDING => ECO:0000269|PubMed:28546513, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI2 30) chain C residue 128 type BINDING sequence C description BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI3 31) chain C residue 135 type BINDING sequence C description BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI3 32) chain C residue 147 type BINDING sequence H description BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI3 33) chain C residue 152 type BINDING sequence H description BINDING => ECO:0000269|PubMed:16085652, ECO:0000269|PubMed:28546513, ECO:0007744|PDB:2A25, ECO:0007744|PDB:5WZZ source Swiss-Prot : SWS_FT_FI3

Display surface Download Links