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eF-site ID
|
4hwy-A |
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PDB Code
|
4hwy |
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Chain
|
A |
|
click to enlarge
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Title
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Trypanosoma brucei procathepsin B solved from 40 fs free-electron laser pulse data by serial femtosecond X-ray crystallography |
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Classification
|
HYDROLASE |
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Compound
|
Cysteine peptidase C (CPC) |
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Source
|
Trypanosoma brucei brucei (strain 927/4 GUTat10.1) (D6XHE1_TRYB2) |
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Sequence
|
A: |
EDAPVLSKAFVDRVNRLNRGIWKAKYDGVMQNITLREAKR
LNGVIKILPKRRFTEEEARAPLPSSFDSAEAWPNCPTIPQ
IADQSACGSCWAVAAASAMSDRFCTMGGVQDVHISAGDLL
ACCSDCGDGCNGGDPDRAWAYFSSTGLVSDYCQPYPFPHC
SHHSKSKNGYPPCSQFNFDTPKCNYTCDDPTIPVVNYRSW
TSYALQGEDDYMRELFFRGPFEVAFDVYEDFIAYNSGVYH
HVSGQYLGGHAVRLVGWGTSNGVPYWKIANSWNTEWGMDG
YFLIRRGSSECGIEDGGSAGIPLAPNTA
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Description
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Functional site
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|
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1)
|
chain |
A |
| residue |
116-127 |
| type |
prosite |
| sequence |
QSACGSCWAVAA
|
| description |
THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QSaCGSCWAvAA
|
| source |
prosite : PS00139
|
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2)
|
chain |
A |
| residue |
280-290 |
| type |
prosite |
| sequence |
GGHAVRLVGWG
|
| description |
THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. GGHAVRLVGWG
|
| source |
prosite : PS00639
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