eF-site ID 4hna-B PDB Code 4hna Chain B click to enlarge Title Kinesin motor domain in the ADP-MG-ALFX state in complex with tubulin and a DARPIN Classification MOTOR PROTEIN Compound Tubulin alpha chain Source ORGANISM_COMMON: domestic sheep,lambs,wild sheep; ORGANISM_SCIENTIFIC: Ovis aries; Sequence B:  MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDS DLQLERINVYYNEATGNKYVPRAILVDLEPGTMDSVRSGP FGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYP DRIMNTFSVMPSPKVSDTVVEPYNATLSVHQLVENTDETY SIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQ YRALTVPELTQQMFDSKNMMAACDPRHGRYLTVAAIFRGR MSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTG EGMDEMEFTEAESNMNDLVSEYQQYQDATAD Description Functional site 1) chain B residue 254 type sequence K description BINDING SITE FOR RESIDUE GTP A 600 source : AC1 2) chain B residue 10 type sequence G description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 3) chain B residue 11 type sequence Q description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 4) chain B residue 12 type sequence C description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 5) chain B residue 15 type sequence Q description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 6) chain B residue 140 type sequence S description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 7) chain B residue 143 type sequence G description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 8) chain B residue 144 type sequence G description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 9) chain B residue 145 type sequence T description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 10) chain B residue 146 type sequence G description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 11) chain B residue 177 type sequence V description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 12) chain B residue 178 type sequence S description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 13) chain B residue 183 type sequence E description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 14) chain B residue 206 type sequence N description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 15) chain B residue 224 type sequence Y description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 16) chain B residue 228 type sequence N description BINDING SITE FOR RESIDUE GDP B 501 source : AC3 17) chain B residue 11 type sequence Q description BINDING SITE FOR RESIDUE MG B 502 source : AC4 18) chain B residue 71 type sequence E description BINDING SITE FOR RESIDUE MG B 502 source : AC4 19) chain B residue 71 type sequence E description BINDING SITE FOR RESIDUE ALF B 503 source : AC5 20) chain B residue 99 type sequence A description BINDING SITE FOR RESIDUE ALF B 503 source : AC5 21) chain B residue 100 type sequence G description BINDING SITE FOR RESIDUE ALF B 503 source : AC5 22) chain B residue 101 type sequence N description BINDING SITE FOR RESIDUE ALF B 503 source : AC5 23) chain B residue 144 type sequence G description BINDING SITE FOR RESIDUE ALF B 503 source : AC5 24) chain B residue 145 type sequence T description BINDING SITE FOR RESIDUE ALF B 503 source : AC5 25) chain B residue 142-148 type prosite sequence GGGTGSG description TUBULIN Tubulin subunits alpha, beta, and gamma signature. GGGTGSG source prosite : PS00227 26) chain B residue 1-4 type prosite sequence MREI description TUBULIN_B_AUTOREG Tubulin-beta mRNA autoregulation signal. MREI source prosite : PS00228

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