eF-site ID 4hlm-B PDB Code 4hlm Chain B click to enlarge Title Crystal structure of Tankyrase 2 in complex with 3',4'-Dihydroxyflavone Classification TRANSFERASE Compound Tankyrase-2 Source (TNKS2_HUMAN) Sequence B:  GTILIDLSPDDKEFQSVEEEMQSTVREHRDGGHAGGIFNR YNILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLFH GSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQY VYGIGGGTGCPVHKDRSCYICHRQLLFCRVTLGKSFLQFS AM Description Functional site 1) chain B residue 1081 type sequence C description BINDING SITE FOR RESIDUE ZN B 1201 source : AC6 2) chain B residue 1084 type sequence H description BINDING SITE FOR RESIDUE ZN B 1201 source : AC6 3) chain B residue 1089 type sequence C description BINDING SITE FOR RESIDUE ZN B 1201 source : AC6 4) chain B residue 1092 type sequence C description BINDING SITE FOR RESIDUE ZN B 1201 source : AC6 5) chain B residue 977 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1202 source : AC7 6) chain B residue 979 type sequence H description BINDING SITE FOR RESIDUE SO4 B 1202 source : AC7 7) chain B residue 980 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1202 source : AC7 8) chain B residue 1067 type sequence K description BINDING SITE FOR RESIDUE SO4 B 1202 source : AC7 9) chain B residue 1070 type sequence Q description BINDING SITE FOR RESIDUE SO4 B 1202 source : AC7 10) chain B residue 990 type sequence N description BINDING SITE FOR RESIDUE SO4 B 1203 source : AC8 11) chain B residue 991 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1203 source : AC8 12) chain B residue 1031 type sequence H description BINDING SITE FOR RESIDUE 16S B 1204 source : AC9 13) chain B residue 1032 type sequence G description BINDING SITE FOR RESIDUE 16S B 1204 source : AC9 14) chain B residue 1033 type sequence S description BINDING SITE FOR RESIDUE 16S B 1204 source : AC9 15) chain B residue 1050 type sequence Y description BINDING SITE FOR RESIDUE 16S B 1204 source : AC9 16) chain B residue 1060 type sequence Y description BINDING SITE FOR RESIDUE 16S B 1204 source : AC9 17) chain B residue 1067 type sequence K description BINDING SITE FOR RESIDUE 16S B 1204 source : AC9 18) chain B residue 1068 type sequence S description BINDING SITE FOR RESIDUE 16S B 1204 source : AC9 19) chain B residue 1071 type sequence Y description BINDING SITE FOR RESIDUE 16S B 1204 source : AC9 20) chain B residue 1081 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 21) chain B residue 1084 type BINDING sequence H description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 22) chain B residue 1089 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1 23) chain B residue 1092 type BINDING sequence C description BINDING => ECO:0000250|UniProtKB:O95271 source Swiss-Prot : SWS_FT_FI1

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