|
|
eF-site ID
|
4hfw-ABHL |
|
PDB Code
|
4hfw |
|
Chain
|
A, B, H, L |
|
click to enlarge
|
|
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Title
|
Anti Rotavirus Antibody |
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Classification
|
IMMUNE SYSTEM |
|
Compound
|
6-26 Fab Light chain |
|
Source
|
(4HFW) |
|
|
Sequence
|
A: |
IRLTQSPSSLSASVGDRVTITCRASQSISNYLNWYQKKPG
QAPKLLIYAATSLQSGVPSRFSGSGSGTDFTLTISSVQPE
DFATYYCQKTLRTWTFGQGTKVEIKRTAAAPSVFIFPPSD
EQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQES
VTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLS
SPVTKSFNRG
|
| B: |
EFQLVESGAEVKKPGASVKVSCKASGYSFTSYYVHWVREA
PGEGLEWMGMINPSDGSTYYAQRFQPRVTMTRDTSTTTVF
MEMSGLRSEDTAVYYCARGVVGATNEIDFWGQGTTVTVSS
ASFKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVS
WNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQT
YICNVNHKPSNTKVDKKVEPK
|
| H: |
EFQLVESGAEVKKPGASVKVSCKASGYSFTSYYVHWVREA
PGEGLEWMGMINPSDGSTYYAQRFQPRVTMTRDTSTTTVF
MEMSGLRSEDTAVYYCARGVVGATNEIDFWGQGTTVTVSS
ASFKGPSVFPLAPSGTAALGCLVKDYFPEPVTVSWNSGAL
TSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVN
HKPSNTKVDKKVEP
|
| L: |
DIRLTQSPSSLSASVGDRVTITCRASQSISNYLNWYQKKP
GQAPKLLIYAATSLQSGVPSRFSGSGSGTDFTLTISSVQP
EDFATYYCQKTLRTWTFGQGTKVEIKRTAAAPSVFIFPPS
DEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQE
SVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGL
SSPVTKSFNRGE
|
|
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Description
|
(1) |
6-26 Fab Light chain, 6-26 Fab Heavy chain
|
|
Functional site
|
|
|
1)
|
chain |
H |
| residue |
87 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE SO4 H 301
|
| source |
: AC1
|
|
|
2)
|
chain |
H |
| residue |
88 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE SO4 H 301
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
2 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE SO4 A 301
|
| source |
: AC2
|
|
|
4)
|
chain |
A |
| residue |
90 |
| type |
|
| sequence |
K
|
| description |
BINDING SITE FOR RESIDUE SO4 A 301
|
| source |
: AC2
|
|
|
5)
|
chain |
A |
| residue |
93 |
| type |
|
| sequence |
R
|
| description |
BINDING SITE FOR RESIDUE SO4 A 301
|
| source |
: AC2
|
|
|
6)
|
chain |
A |
| residue |
94 |
| type |
|
| sequence |
T
|
| description |
BINDING SITE FOR RESIDUE SO4 A 301
|
| source |
: AC2
|
|
|
7)
|
chain |
H |
| residue |
201-207 |
| type |
prosite |
| sequence |
YICNVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
|
|
|
8)
|
chain |
L |
| residue |
191-197 |
| type |
prosite |
| sequence |
YACEVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
|
| source |
prosite : PS00290
|
|
|
|