eF-site ID 4hee-XY PDB Code 4hee Chain X, Y click to enlarge Title Crystal structure of PPARgamma in complex with compound 13 Classification TRANSCRIPTION/TRANSCRIPTION INHIBITOR Compound Peroxisome proliferator-activated receptor gamma Source Homo sapiens (Human) (NCOA1_HUMAN) Sequence X:  ADLRALAKHLYDSYIKSFPLTKAKARAILTGKKSPFVIYD MNSLMMGEDKEVAIRIFQGCQFRSVEAVQEITEYAKSIPG FVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQ GFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLA IFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNH PESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSL HPLLQEIYKDL Y:  TERHKILHRLLQEGSP Description Functional site 1) chain X residue 284 type sequence G description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 2) chain X residue 285 type sequence C description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 3) chain X residue 288 type sequence R description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 4) chain X residue 289 type sequence S description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 5) chain X residue 323 type sequence H description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 6) chain X residue 326 type sequence I description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 7) chain X residue 327 type sequence Y description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 8) chain X residue 339 type sequence V description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 9) chain X residue 340 type sequence L description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 10) chain X residue 341 type sequence I description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 11) chain X residue 342 type sequence S description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 12) chain X residue 367 type sequence K description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 13) chain X residue 449 type sequence H description BINDING SITE FOR RESIDUE 14R X 501 source : AC1 14) chain Y residue 698 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 15) chain X residue 323 type MOD_RES sequence H description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 16) chain X residue 449 type MOD_RES sequence H description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 17) chain X residue 473 type MOD_RES sequence Y description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 18) chain X residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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