eF-site ID 4hcc-B PDB Code 4hcc Chain B click to enlarge Title The zinc ion bound form of crystal structure of E.coli ExoI-ssDNA complex Classification HYDROLASE/DNA Compound Exodeoxyribonuclease I Source Escherichia coli (strain K12) (4HCC) Sequence B:  QSTFLFHDYETFGTHPALDRPAQFAAIRTDSEFNVIGEPE VFYCKPADDYLPQPGAVLITGITPQEARAKGENEAAFAAR IHSLFTVPKTCILGYNNVRFDDEVTRNIFYRNFYDPYAWS WQHDNSRWDLLDVMRACYALRPEGINWPENLPSFRLEHLT KANGIEHSNAHDAMADVYATIAMAKLVKTRQPRLFDYLFT HRNKHKLMALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLA WHPENRNAVIMVDLAGDISPLLELDSDTLRERLYTAKTDL GDNAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHC LDNLKILRENPQVREKVVAIFAEFTPSDNVDAQLYNGFFS DADRAAMKIVLETEPRNLPALDITFVDKRIEKLLFNYRAR NFPGTLDYAEQQRWLEHRRQVFTPEFLQGYADELQMLVQQ YADDKEKVALLKALWQYADEIVH Description Functional site 1) chain B residue 178 type sequence S description BINDING SITE FOR RESIDUE SO4 A 503 source : AC3 2) chain B residue 179 type sequence N description BINDING SITE FOR RESIDUE SO4 A 503 source : AC3 3) chain B residue 214 type sequence K description BINDING SITE FOR RESIDUE SO4 B 501 source : AC6 4) chain B residue 215 type sequence H description BINDING SITE FOR RESIDUE SO4 B 501 source : AC6 5) chain B residue 256 type sequence R description BINDING SITE FOR RESIDUE SO4 B 501 source : AC6 6) chain B residue 438 type sequence E description BINDING SITE FOR RESIDUE SO4 B 502 source : AC7 7) chain B residue 106 type sequence R description BINDING SITE FOR RESIDUE SO4 B 503 source : AC8 8) chain B residue 233 type sequence S description BINDING SITE FOR RESIDUE SO4 B 503 source : AC8 9) chain B residue 235 type sequence M description BINDING SITE FOR RESIDUE SO4 B 503 source : AC8 10) chain B residue 299 type sequence K description BINDING SITE FOR RESIDUE SO4 B 503 source : AC8 11) chain B residue 11 type sequence F description BINDING SITE FOR RESIDUE SO4 B 504 source : AC9 12) chain B residue 198 type sequence K description BINDING SITE FOR RESIDUE SO4 B 504 source : AC9 13) chain B residue 205 type sequence F description BINDING SITE FOR RESIDUE SO4 B 504 source : AC9 14) chain B residue 206 type sequence D description BINDING SITE FOR RESIDUE SO4 B 504 source : AC9 15) chain B residue 209 type sequence F description BINDING SITE FOR RESIDUE SO4 B 504 source : AC9 16) chain B residue 15 type sequence D description BINDING SITE FOR RESIDUE ZN B 505 source : BC1 17) chain B residue 17 type sequence E description BINDING SITE FOR RESIDUE ZN B 505 source : BC1 18) chain B residue 186 type sequence D description BINDING SITE FOR RESIDUE ZN B 505 source : BC1 19) chain B residue 446 type sequence E description BINDING SITE FOR RESIDUE IPA B 506 source : BC2 20) chain B residue 18 type sequence T description BINDING SITE FOR RESIDUE IPA B 507 source : BC3 21) chain B residue 15 type sequence D description BINDING SITE FOR RESIDUE PO4 D 101 source : BC5 22) chain B residue 17 type sequence E description BINDING SITE FOR RESIDUE PO4 D 101 source : BC5 23) chain B residue 181 type sequence H description BINDING SITE FOR RESIDUE PO4 D 101 source : BC5 24) chain B residue 186 type sequence D description BINDING SITE FOR RESIDUE PO4 D 101 source : BC5 25) chain B residue 17 type BINDING sequence E description BINDING => ECO:0000269|PubMed:18219121 source Swiss-Prot : SWS_FT_FI2 26) chain B residue 165 type BINDING sequence R description BINDING => ECO:0000269|PubMed:18219121 source Swiss-Prot : SWS_FT_FI2 27) chain B residue 186 type BINDING sequence D description BINDING => ECO:0000269|PubMed:18219121 source Swiss-Prot : SWS_FT_FI2 28) chain B residue 338 type SITE sequence R description Important for interaction with ssb => ECO:0000305|PubMed:20018747 source Swiss-Prot : SWS_FT_FI7 29) chain B residue 15 type BINDING sequence D description BINDING => ECO:0000269|PubMed:11101894, ECO:0000269|PubMed:18219121, ECO:0000269|PubMed:18591666, ECO:0000269|PubMed:20018747, ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI1 30) chain B residue 18 type SITE sequence T description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI3 31) chain B residue 66 type SITE sequence I description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI3 32) chain B residue 113 type SITE sequence R description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI3 33) chain B residue 124 type SITE sequence Y description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI3 34) chain B residue 128 type SITE sequence W description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI3 35) chain B residue 142 type SITE sequence R description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI3 36) chain B residue 214 type SITE sequence K description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI3 37) chain B residue 284 type SITE sequence Y description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI3 38) chain B residue 368 type SITE sequence Y description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI3 39) chain B residue 371 type SITE sequence F description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI3 40) chain B residue 148 type SITE sequence R description Important for interaction with ssb => ECO:0000269|PubMed:18591666 source Swiss-Prot : SWS_FT_FI4 41) chain B residue 207 type SITE sequence Y description Important for interaction with ssb => ECO:0000269|PubMed:18591666 source Swiss-Prot : SWS_FT_FI4 42) chain B residue 311 type SITE sequence Q description Important for interaction with ssb => ECO:0000269|PubMed:18591666 source Swiss-Prot : SWS_FT_FI4 43) chain B residue 164 type SITE sequence F description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540, ECO:0007744|PDB:4HCC source Swiss-Prot : SWS_FT_FI5 44) chain B residue 257 type SITE sequence N description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540, ECO:0007744|PDB:4HCC source Swiss-Prot : SWS_FT_FI5 45) chain B residue 304 type SITE sequence N description Interaction with single-stranded DNA => ECO:0000269|PubMed:23609540, ECO:0007744|PDB:4HCC source Swiss-Prot : SWS_FT_FI5 46) chain B residue 181 type SITE sequence H description Important for activity => ECO:0000269|PubMed:23609540 source Swiss-Prot : SWS_FT_FI6

Display surface Download Links