eF-site ID 4hbt-A PDB Code 4hbt Chain A click to enlarge Title Crystal structure of native CTX-M-15 extended-spectrum beta-lactamase Classification HYDROLASE Compound Beta-lactamase Source (Q9EXV5_ECOLX) Sequence A:  TADVQQKLAELERQSGGRLGVALINTADNSQILYRADERF AMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKKSDLVNYN PIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPA SVTAFARQLGDETFRLDRTEPTLNTAIPGDPRDTTSPRAM AQTLRNLTLGKALGDSQRAQLVTWMKGNTTGAASIQAGLP ASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQP QPKAESRRDVLASAAKIVTDGL Description Functional site 1) chain A residue 70 type sequence S description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 2) chain A residue 130 type sequence S description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 3) chain A residue 235 type sequence T description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 4) chain A residue 236 type sequence G description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 5) chain A residue 237 type sequence S description BINDING SITE FOR RESIDUE SO4 A 301 source : AC1 6) chain A residue 82 type sequence K description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 7) chain A residue 164 type sequence R description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 8) chain A residue 168 type sequence T description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 9) chain A residue 178 type sequence R description BINDING SITE FOR RESIDUE SO4 A 302 source : AC2 10) chain A residue 98 type sequence K description BINDING SITE FOR RESIDUE SO4 A 303 source : AC3 11) chain A residue 99 type sequence K description BINDING SITE FOR RESIDUE SO4 A 303 source : AC3 12) chain A residue 100 type sequence S description BINDING SITE FOR RESIDUE SO4 A 303 source : AC3 13) chain A residue 98 type sequence K description BINDING SITE FOR RESIDUE SO4 A 304 source : AC4 14) chain A residue 153 type sequence R description BINDING SITE FOR RESIDUE SO4 A 304 source : AC4 15) chain A residue 197 type sequence K description BINDING SITE FOR RESIDUE SO4 A 304 source : AC4 16) chain A residue 39 type sequence R description BINDING SITE FOR RESIDUE SO4 A 305 source : AC5 17) chain A residue 272 type sequence S description BINDING SITE FOR RESIDUE SO4 A 305 source : AC5 18) chain A residue 274 type sequence R description BINDING SITE FOR RESIDUE SO4 A 305 source : AC5 19) chain A residue 63 type sequence D description BINDING SITE FOR RESIDUE EDO A 306 source : AC6 20) chain A residue 83 type sequence K description BINDING SITE FOR RESIDUE EDO A 306 source : AC6 21) chain A residue 87 type sequence E description BINDING SITE FOR RESIDUE EDO A 306 source : AC6 22) chain A residue 90 type sequence L description BINDING SITE FOR RESIDUE EDO A 306 source : AC6 23) chain A residue 93 type sequence Q description BINDING SITE FOR RESIDUE EDO A 306 source : AC6 24) chain A residue 141 type sequence H description BINDING SITE FOR RESIDUE EDO A 306 source : AC6 25) chain A residue 184 type sequence R description BINDING SITE FOR RESIDUE EDO A 306 source : AC6 26) chain A residue 79 type sequence A description BINDING SITE FOR RESIDUE EDO A 307 source : AC7 27) chain A residue 151 type sequence F description BINDING SITE FOR RESIDUE EDO A 307 source : AC7 28) chain A residue 59 type sequence L description BINDING SITE FOR RESIDUE EDO A 308 source : AC8 29) chain A residue 61 type sequence R description BINDING SITE FOR RESIDUE EDO A 308 source : AC8 30) chain A residue 62 type sequence A description BINDING SITE FOR RESIDUE EDO A 308 source : AC8 31) chain A residue 63 type sequence D description BINDING SITE FOR RESIDUE EDO A 308 source : AC8 32) chain A residue 51 type sequence N description BINDING SITE FOR RESIDUE EDO A 309 source : AC9 33) chain A residue 104 type sequence N description BINDING SITE FOR RESIDUE EDO A 309 source : AC9 34) chain A residue 167 type sequence P description BINDING SITE FOR RESIDUE EDO A 309 source : AC9 35) chain A residue 288 type sequence L description BINDING SITE FOR RESIDUE EDO A 309 source : AC9 36) chain A residue 50 type sequence I description BINDING SITE FOR RESIDUE EDO A 310 source : BC1 37) chain A residue 55 type sequence N description BINDING SITE FOR RESIDUE EDO A 310 source : BC1 38) chain A residue 147 type sequence S description BINDING SITE FOR RESIDUE EDO A 310 source : BC1 39) chain A residue 188 type sequence Q description BINDING SITE FOR RESIDUE EDO A 310 source : BC1 40) chain A residue 191 type sequence R description BINDING SITE FOR RESIDUE EDO A 310 source : BC1 41) chain A residue 100 type sequence S description BINDING SITE FOR RESIDUE EDO A 311 source : BC2 42) chain A residue 191 type sequence R description BINDING SITE FOR RESIDUE EDO A 311 source : BC2 43) chain A residue 195 type sequence L description BINDING SITE FOR RESIDUE EDO A 311 source : BC2 44) chain A residue 44 type sequence R description BINDING SITE FOR RESIDUE EDO A 312 source : BC3 45) chain A residue 61 type sequence R description BINDING SITE FOR RESIDUE EDO A 312 source : BC3 46) chain A residue 115 type sequence G description BINDING SITE FOR RESIDUE EDO A 313 source : BC4 47) chain A residue 116 type sequence T description BINDING SITE FOR RESIDUE EDO A 313 source : BC4 48) chain A residue 202 type sequence S description BINDING SITE FOR RESIDUE EDO A 313 source : BC4 49) chain A residue 203 type sequence Q description BINDING SITE FOR RESIDUE EDO A 313 source : BC4 50) chain A residue 206 type sequence Q description BINDING SITE FOR RESIDUE EDO A 313 source : BC4 51) chain A residue 227 type sequence A description BINDING SITE FOR RESIDUE CL A 314 source : BC5 52) chain A residue 267 type sequence Q description BINDING SITE FOR RESIDUE CL A 314 source : BC5 53) chain A residue 269 type sequence K description BINDING SITE FOR RESIDUE CL A 314 source : BC5 54) chain A residue 66-81 type prosite sequence FAMCSTSKVMAAAAVL description BETA_LACTAMASE_A Beta-lactamase class-A active site. FaMCSTsKvmaAAAVL source prosite : PS00146

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