eF-site ID 4hbm-E
PDB Code 4hbm
Chain E

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Title Ordering of the N Terminus of Human MDM2 by Small Molecule Inhibitors
Classification ligase/ligase inhibitor
Compound E3 ubiquitin-protein ligase Mdm2
Source Homo sapiens (Human) (MDM2_HUMAN)
Sequence E:  SVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKD
TYTMKEVLFYLGQYIMTKRLYQHIVYCSNDLLGDLFGVPS
FSVKEHRKIYTMIYRNLVVVN
Description


Functional site

1) chain E
residue 59
type
sequence Q
description BINDING SITE FOR RESIDUE 0Y7 C 201
source : AC3

2) chain E
residue 14
type
sequence V
description BINDING SITE FOR RESIDUE 0Y7 E 201
source : AC5

3) chain E
residue 16
type
sequence T
description BINDING SITE FOR RESIDUE 0Y7 E 201
source : AC5

4) chain E
residue 54
type
sequence L
description BINDING SITE FOR RESIDUE 0Y7 E 201
source : AC5

5) chain E
residue 58
type
sequence G
description BINDING SITE FOR RESIDUE 0Y7 E 201
source : AC5

6) chain E
residue 61
type
sequence I
description BINDING SITE FOR RESIDUE 0Y7 E 201
source : AC5

7) chain E
residue 93
type
sequence V
description BINDING SITE FOR RESIDUE 0Y7 E 201
source : AC5

8) chain E
residue 94
type
sequence K
description BINDING SITE FOR RESIDUE 0Y7 E 201
source : AC5

9) chain E
residue 96
type
sequence H
description BINDING SITE FOR RESIDUE 0Y7 E 201
source : AC5

10) chain E
residue 100
type
sequence Y
description BINDING SITE FOR RESIDUE 0Y7 E 201
source : AC5


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